With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …

Vaccination is one of the most successful measures in modern medicine to combat
diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …

Current worldwide mRNA vaccination against SARS-CoV-2 by intramuscular injection using
a needled syringe has greatly protected numerous people from COVID-19. An intramuscular …

The COVID-19 pandemic has underscored the pressing need for safe and effective booster
vaccines, particularly in considering the emergence of new SARS-CoV-2 variants and …

In August 2022, Italy launched a vaccination campaign to combat the spread of the
monkeypox virus, which the WHO has designated as a public health emergency. Priority …

Since the skin limits the distribution of intradermal vaccines, a large number of dendritic cells
in the skin cannot be fully utilized to elicit a more effective immune response. Here, we …

Current influenza vaccines mainly induce neutralizing antibodies against the highly variable
surface antigen hemagglutinin and require annual manufacturing and immunization …

Lung cancer is a highly lethal malignancy that poses a significant burden on public health
worldwide. There have been numerous therapeutic approaches, among which cancer …

Introduction Colorectal cancer (CRC) is the second most lethal malignancy worldwide.
Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair …

MF59 and AS03 are squalene emulsion-based vaccine adjuvants with similar compositions
and droplet sizes. Despite their broad use in licensed influenza vaccines, few studies …