The small molecule fibroblast growth factor receptor inhibitor infigratinib exerts anti‐inflammatory effects and remyelination in a model of multiple sclerosis

R Rajendran, V Rajendran, G Böttiger… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Fibroblast growth factors and receptors (FGFR) have
been shown to modulate inflammation and neurodegeneration in multiple sclerosis (MS) …

Ozanimod to treat relapsing forms of multiple sclerosis: a comprehensive review of disease, drug efficacy and side effects

G Lassiter, C Melancon, T Rooney, AM Murat… - Neurology …, 2020 - mdpi.com
Multiple sclerosis (MS) is a prevalent and debilitating neurologic condition characterized by
widespread neurodegeneration and the formation of focal demyelinating plaques in the …

S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple …

SF Ahmad, MA Ansari, A Nadeem, SA Bakheet… - Multiple Sclerosis and …, 2023 - Elsevier
CD4+ T cells, specifically Th cells (Th1 and Th17) and regulatory T cells (Tregs), play a
pivotal role in the pathogenesis of multiple sclerosis (MS), a demyelinating autoimmune …

The epidemiology of primary headaches in patients with multiple sclerosis

L Wang, J Zhang, ZR Deng, MD Zu… - Brain and Behavior, 2021 - Wiley Online Library
Objective Recent studies have shown a pathophysiologic link between headache and
multiple sclerosis (MS), but the prevalence of primary headaches among patients with MS …

A quantitative synthesis of eight decades of global multiple sclerosis research using bibliometrics

II Ismail, M Saqr - Frontiers in Neurology, 2022 - frontiersin.org
Bibliometric studies on the field of multiple sclerosis (MS) research are scarce. The aim of
this study is to offer an overarching view of the body of knowledge about MS research over …

Role of thyroid hormones in normal and abnormal central nervous system myelination in humans and rodents

M Pagnin, D Kondos-Devcic, G Chincarini… - Frontiers in …, 2021 - Elsevier
Thyroid hormones (THs) are instrumental in promoting the molecular mechanisms which
underlie the complex nature of neural development and function within the central nervous …

Innate lymphoid cells-neglected players in multiple sclerosis

N Sadeghi Hassanabadi, B Broux, S Marinović… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a highly debilitating autoimmune disease affecting millions of
individuals worldwide. Although classically viewed as T-cell mediated disease, the role of …

The effect of Urtica dioica extract on oxidative stress, heat shock proteins, and brain histopathology in multiple sclerosis model

F Namazi, E Bordbar, F Bakhshaei… - Physiological …, 2022 - Wiley Online Library
Multiple sclerosis (MS) results from the destruction of myelin and focal inflammation. The
study aimed to evaluate the effect of hydroalcoholic extract of Urtica dioica on oxidative …

The role of microRNAs involved in the disorder of blood–brain barrier in the pathogenesis of multiple sclerosis

A Emami Nejad, SM Mostafavi Zadeh… - Frontiers in …, 2023 - frontiersin.org
miRNAs are involved in various vital processes, including cell growth, development,
apoptosis, cellular differentiation, and pathological cellular activities. Circulating miRNAs …

Effects of venlafaxine, risperidone and febuxostat on cuprizone-induced demyelination, behavioral deficits and oxidative stress

DP Mihai, A Ungurianu, CI Ciotu, MJM Fischer… - International Journal of …, 2021 - mdpi.com
Multiple sclerosis (MS) is a demyelinating, autoimmune disease that affects a large number
of young adults. Novel therapies for MS are needed considering the efficiency and safety …