Rheumatoid arthritis (RA) is an autoimmune inflammatory systematic complication which is a
chronic disorder that severely affects bones and joints and results in the quality of life …

Ferroptosis is one of the main mechanisms involved in different forms of acute kidney injury
(AKI), including cisplatin-induced AKI. However, it is not clear whether Cx43 has a regulatory …

Background To examine the levels of exosome-derived connexin 43 (Cx43) in plasma and
estimate its forecast value in patients with melanoma. Methods We measured the plasma …

Objective: Periodontitis is a common chronic inflammatory disease in which oxidative stress
is one of the key pathogenic factors. Connexin43 (Cx43) is the most critical and widely …

Perfluorooctane sulfonate (PFOS) is a persistent organic pollutant that can cause
nephrotoxicity. However, the underlying mechanisms are not fully understood and require …

Cadmium (Cd) as a ubiquitous toxic heavy metal is reported to affect the nervous system.
Selenium (Se) has been shown to have antagonistic effects against heavy metal toxicity. In …

Protracted use of paracetamol at therapeutic/toxic doses readily induces major organ toxicity
and poor clinical efficacy. Caesalpinia bonducella seeds possess a diverse range of …

Isovitexin (IVT) has been shown to have a potential therapeutic effect on acute liver injury
(ALI), but its underlying mechanisms especially the targets remain unclear, which was …

Magnesium isoglycyrrhizinate (MgIG) has anti-inflammatory, antioxidative, antiviral and anti-
hepatotoxic effects. However, protective effects of MgIG against renal damage caused by …

Intercellular communication between the cell plays an essential role in cell growth and cell
formation, including migration, metabolism, and cell differentiation. Cell function and tissue …