Anti-fibrotic effects of statin drugs: A review of evidence and mechanisms

DM Dolivo, CR Reed, KA Gargiulo… - Biochemical …, 2023 - Elsevier
Fibrosis is a pathological repair process common among organs, that responds to damage
by replacement of tissue with non-functional connective tissue. Despite the widespread …

Determinants of market exclusivity for prescription drugs in the United States

AS Kesselheim, MS Sinha, J Avorn - JAMA internal medicine, 2017 - jamanetwork.com
The high prices of brand-name prescription drugs are a growing source of controversy in the
United States. Manufacturers of brand-name drugs can command high prices because they …

Comparing generic drug markets in Europe and the United States: prices, volumes, and spending

OJ Wouters, PG Kanavos, M McKee - The Milbank Quarterly, 2017 - Wiley Online Library
Policy Points: Our study indicates that there are opportunities for cost savings in generic
drug markets in Europe and the United States. Regulators should make it easier for generic …

[HTML][HTML] Defining and measuring health poverty

P Clarke, G Erreygers - Social science & medicine, 2020 - Elsevier
Unlike other aspects of welfare (eg income), health has been relatively neglected when it
comes to defining and measuring aspects of poverty. The aim of the paper is twofold: first we …

Trends in use of high-intensity statin therapy after myocardial infarction, 2011 to 2014

RS Rosenson, ME Farkouh, M Mefford, V Bittner… - Journal of the American …, 2017 - jacc.org
Background: Data prior to 2011 suggest that a low percentage of patients hospitalized for
acute coronary syndromes filled high-intensity statin prescriptions upon discharge. Black …

[HTML][HTML] Statins utilization trends and expenditures in the US before and after the implementation of the 2013 ACC/AHA guidelines

A Matyori, CP Brown, A Ali, F Sherbeny - Saudi Pharmaceutical Journal, 2023 - Elsevier
Importance Statins are drugs of choice in treating hyperlipidemia and preventing or reducing
cardiovascular diseases. Purpose Explore statins utilization and expenditure trends in the …

Generic drugs in the United States: policies to address pricing and competition

R Gupta, ND Shah, JS Ross - Clinical Pharmacology & …, 2019 - Wiley Online Library
The cost of prescription drugs in the United States continues to be a source of concern for
patients, caregivers, and policymakers. Drug prices typically decline rapidly once generic …

Trends in use and expenditures for brand-name statins after introduction of generic statins in the US, 2002-2018

S Lin, K Baumann, C Zhou, W Zhou… - JAMA network …, 2021 - jamanetwork.com
Importance The high and increasing expenditures for prescription medications in the US is a
national problem. Objective To explore the association of generic statin competition on …

Twenty-year nationwide trends in statin utilization and expenditure in Denmark

MB Mortensen, E Falk, M Schmidt - … : Cardiovascular Quality and …, 2017 - Am Heart Assoc
In Denmark, statin therapy has increased tremendously over the past 20 years with great
variability in the proportionate use of different types of statins. Somewhat surprisingly, total …

[PDF][PDF] Journey of generic imatinib: a case study in oncology drug pricing

CT Chen, AS Kesselheim - Journal of oncology practice, 2017 - scholar.archive.org
In February 2016, a generic version of imatinib (Gleevec), the groundbreaking tyrosine
kinase inhibitor, was made available in the United States. Imatinib has ushered in a new era …