Spirocyclic motifs are emerging privileged structures for drug discovery. They are also
omnipresent in the natural products domain. However, until today, no attempt to analyze the …

Gelsemium elegans Benth (GEB), also known as heartbreak grass, is a highly poisonous
plant belonging to the family Loganiaceae and genus Gelsemium that has broad application …

We report asymmetric [4+ 3] annulations between isatin-derived Morita–Baylis–Hillman
carbonates and two types of vinyl carbonates synergistically catalyzed by tertiary amines …

Monoterpenoid indole alkaloids (MIAs) represent a major class of active ingredients from the
plants of the genus Gelsemium. Gelsemium MIAs with diverse chemical structures can be …

Stroke, especially ischemic stroke, is an important cause of neurological morbidity and
mortality worldwide. Growing evidence suggests that the immune system plays an intricate …

Gelsemium elegans Benth.(G. elegans) is a traditional medicinal herb that has anti-
inflammatory, analgesic, sedative, and detumescence effects. However, it can also cause …

Abstract Characterization of alkaloids and new compound discovery become increasing
challenging for Gelsemium elegans Benth.(G. elegans), due to the lack of an effective …

Covering: up to 2024This review aims to draw a parallel between all known oligomers of
monoterpene indole alkaloids (MIAs) by illustrating the chemical logic underlying their …

Background: The herbal pairing of Dangshen (DS)[Codonopsis pilosula (Franch.) Nannf.]
and Huangqi (HQ)[Astragalus membranaceus (Fisch.) Bge.](DHP) is a traditional Chinese …

Gelsemium elegans Benth.(GEB) exhibits immunoregulatory and growth-promoting effects
in animals. However, owing to its complex composition, the specific mechanism remains to …