Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems
TH Baryakova, BH Pogostin, R Langer… - Nature Reviews Drug …, 2023 - nature.com
Poor medication adherence is a pervasive issue with considerable health and
socioeconomic consequences. Although the underlying reasons are generally understood …
socioeconomic consequences. Although the underlying reasons are generally understood …
Intranasal drug delivery: opportunities and toxicologic challenges during drug development
LA Keller, O Merkel, A Popp - Drug delivery and translational research, 2022 - Springer
Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has
increased. This review article summarises information on intranasal administration for local …
increased. This review article summarises information on intranasal administration for local …
Alginate as a promising biopolymer in drug delivery and wound healing: A review of the state-of-the-art
Biopolymeric nanoparticulate systems hold favorable carrier properties for active delivery.
The enhancement in the research interest in alginate formulations in biomedical and …
The enhancement in the research interest in alginate formulations in biomedical and …
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …
results in a partially crystallized lipid system and imparts many advantages over solid lipid …
Recent advances in the development of in situ gelling drug delivery systems for non-parenteral administration routes
In situ gelling drug delivery systems have gained enormous attention over the last decade.
They are in a sol-state before administration, and they are capable of forming gels in …
They are in a sol-state before administration, and they are capable of forming gels in …
Recent advances in intranasal liposomes for drug, gene, and vaccine delivery
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
produced from cholesterol and phospholipids. Recently, liposomes have been widely …
Nasal route for vaccine and drug delivery: Features and current opportunities
YL Mato - International journal of pharmaceutics, 2019 - Elsevier
Mucosal administration, and specifically nasal route, constitutes an alternative and
promising strategy for drug and vaccine delivery. Mucosal routes have several advantages …
promising strategy for drug and vaccine delivery. Mucosal routes have several advantages …
Current state and future directions of intranasal delivery route for central nervous system disorders: a scientometric and visualization analysis
Background: The management of various central nervous system (CNS) disorders has been
challenging, due to highly compact blood-brain barrier (BBB) impedes the access of most …
challenging, due to highly compact blood-brain barrier (BBB) impedes the access of most …
Design and application in delivery system of intranasal antidepressants
J Xu, J Tao, J Wang - Frontiers in Bioengineering and Biotechnology, 2020 - frontiersin.org
One of the major reasons why depressed patients fail their treatment course is the existence
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …
of the blood-brain barrier (BBB), which prevents drugs from being delivered to the central …