Mitochondria in health, disease, and aging

JS Harrington, SW Ryter, M Plataki… - Physiological …, 2023 - journals.physiology.org
Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Small molecule based fluorescent chemosensors for imaging the microenvironment within specific cellular regions

J Yin, L Huang, L Wu, J Li, TD James… - Chemical Society Reviews, 2021 - pubs.rsc.org
The microenvironment (local environment), including viscosity, temperature, polarity,
hypoxia, and acidic-basic status (pH), plays indispensable roles in cellular processes …

Mitochondria and cancer

S Vyas, E Zaganjor, MC Haigis - Cell, 2016 - cell.com
Mitochondria are bioenergetic, biosynthetic, and signaling organelles that are integral in
stress sensing to allow for cellular adaptation to the environment. Therefore, it is not …

Small-molecule fluorogenic probes for mitochondrial nanoscale imaging

R Zhai, B Fang, Y Lai, B Peng, H Bai, X Liu… - Chemical Society …, 2023 - pubs.rsc.org
Mitochondria are inextricably linked to the development of diseases and cell metabolism
disorders. Super-resolution imaging (SRI) is crucial in enhancing our understanding of …

The role of mitochondria in metabolism and cell death

H Vakifahmetoglu-Norberg, AT Ouchida… - … and biophysical research …, 2017 - Elsevier
Mitochondria are complex organelles that play a central role in energy metabolism, control
of stress responses and are a hub for biosynthetic processes. Beyond its well-established …

A practical guide for the analysis, standardization and interpretation of oxygen consumption measurements

AS Divakaruni, M Jastroch - Nature metabolism, 2022 - nature.com
Measurement of oxygen consumption is a powerful and uniquely informative experimental
technique. It can help identify mitochondrial mechanisms of action following pharmacologic …

Unraveling mitochondria‐targeting reactive oxygen species modulation and their implementations in cancer therapy by nanomaterials

H Peng, F Yao, J Zhao, W Zhang, L Chen, X Wang… - …, 2023 - Wiley Online Library
Functional subcellular organelle mitochondria are emerging as a crucial player and driver of
cancer. For maintaining the sites of cellular respiration, mitochondria experience production …

The advanced role of carbon quantum dots in nanomedical applications

P Devi, S Saini, KH Kim - Biosensors and Bioelectronics, 2019 - Elsevier
Carbon quantum dots (CQDs) have emerged as a potential material in the diverse fields of
biomedical applications due to their numerous advantageous properties including …

Mitochondrial structure and bioenergetics in normal and disease conditions

M Protasoni, M Zeviani - International journal of molecular sciences, 2021 - mdpi.com
Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in aging and cancer

AV Kudryavtseva, GS Krasnov, AA Dmitriev… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Aging and cancer are the most important issues to research. The population in the world is
growing older, and the incidence of cancer increases with age. There is no doubt about the …