Cancer cells undergo metabolic reprogramming and switch to a 'glycolysis-
dominant'metabolic profile to promote their survival and meet their requirements for energy …

Aerobic glycolysis is an emerging hallmark of many human cancers, as cancer cells are
defined as a “metabolically abnormal system”. Carbohydrates are metabolically …

Ferroptosis, featuring an iron‐dependent peroxidation of lipids, is a novel form of
programmed cell death that may hold great potential in cancer therapy. Our study found that …

Simple Summary Glucose metabolic reprogramming is a process in which cells alter the way
that glucose is utilized. In breast cancer, cells can undergo this process to fuel their growth …

Breast cancer (BC) is the most frequently diagnosed cancer and one of the major causes of
cancer death. Despite enormous progress in its management, both from the therapeutic and …

The joint analysis of single-cell transcriptomics, proteomics, lipidomics, metabolomics and
spatial metabolomics is continually transforming our understanding of the mechanisms of …

Background: Fatty acid metabolism (FAM), as a hallmark of caner, plays important roles in
tumor initiation and carcinogenesis. However, the significance of fatty acid metabolism …

Heterogeneity is a complex feature of cells and tissues with many interacting components.
Depending on the nature of the research context, interacting features of cellular, drug …

Prostate cancer (PCa) continues to be one of the most common cancers in men worldwide.
The six transmembrane epithelial antigen of the prostate 1 (STEAP1) protein is …

Age-related macular degeneration (AMD) is characterized by progressive accumulation of
drusen deposits and retinal pigment epithelium (RPE) disorders. As the main component of …