Viral infections are initiated by attachment of the virus to host cell surface receptors,
including sialic acid-containing glycans. It is now possible to rapidly identify specific glycan …

Found throughout biology, polyvalent interactions are characterized by the simultaneous
binding of multiple ligands on one biological entity to multiple receptors on another (top part …

The isolation of broadly neutralizing antibodies against influenza A viruses has been a long-
sought goal for therapeutic approaches and vaccine design. Using a single-cell culture …

▪ Abstract Hemagglutinin (HA) is the receptor-binding and membrane fusion glycoprotein of
influenza virus and the target for infectivity-neutralizing antibodies. The structures of three …

Although human epidemics of influenza occur on nearly an annual basis and result in a
significant number of “excess deaths,” the viruses responsible are not generally considered …

The threat of a major human influenza pandemic, in particular from highly aggressive strains
such as avian H5N1, has emphasized the need for therapeutic strategies to combat these …

We have surveyed avian influenza virus (AIV) genomes from live poultry markets within
China since 2014. Here we present a total of 16,091 samples that were collected from May …

The membrane fusion potential of influenza HA, like many viral membrane-fusion
glycoproteins, is generated by proteolytic cleavage of a biosynthetic precursor. The three …

The hemagglutinin (HA) of influenza A (H3N2) virus responsible for the 1968 influenza
pandemic derived from an avian virus. On introduction into humans, its receptor binding …

This is the second edition of our little red book Lectins published in 1989. In the intervening
years well over 10,000 articles have appeared with lectins as the main subject, and more …