[HTML][HTML] HDAC6 Enhances Endoglin Expression through Deacetylation of Transcription Factor SP1, Potentiating BMP9-Induced Angiogenesis
C Sun, K Xie, L Yang, S Cai, M Wang, Y Zhu, B Tao… - Cells, 2024 - mdpi.com
Histone deacetylase 6 (HDAC6) plays a crucial role in the acetylation of non-histone
proteins and is notably implicated in angiogenesis, though its underlying mechanisms were …
proteins and is notably implicated in angiogenesis, though its underlying mechanisms were …
[HTML][HTML] Role of membrane-bound and circulating endoglin in disease
C Bernabeu, C Olivieri, E Rossi - Frontiers in Medicine, 2023 - frontiersin.org
Since its discovery and characterization in the early 1990s, a growing body of evidence
supports the involvement of endoglin in a broad range of patho-physiological conditions …
supports the involvement of endoglin in a broad range of patho-physiological conditions …
[HTML][HTML] Low Plasma Levels of Soluble Endoglin and Cardiovascular Events in Patients Undergoing Coronary Angiography
E Saita, Y Kishimoto, M Aoyama, R Ohmori, K Kondo… - Biomedicines, 2023 - mdpi.com
TGF-β is recognized as playing a protective role against atherosclerosis. Endoglin is a
receptor for TGF-β, and its expression is upregulated in atherosclerotic plaques. Endoglin is …
receptor for TGF-β, and its expression is upregulated in atherosclerotic plaques. Endoglin is …
Non-canonical regulation of Endoglin by rare and common variants: new molecular and clinical perspectives for Hereditary Hemorrhagic Telangiectasia and beyond
O Soukarieh, G Munsch, C Deiber, C Meguerditchian… - medRxiv, 2024 - medrxiv.org
Endoglin, encoded by the ENG gene, is a transmembrane glycoprotein with a major
implication in angiogenesis. Loss-of function ENG variants are responsible for Hereditary …
implication in angiogenesis. Loss-of function ENG variants are responsible for Hereditary …