Gender differences in cardiovascular disease: hormonal and biochemical influences

FR Pérez-López, L Larrad-Mur, A Kallen… - Reproductive …, 2010 - journals.sagepub.com
Objective: Atherosclerosis is a complex process characterized by an increase in vascular
wall thickness owing to the accumulation of cells and extracellular matrix between the …

Estrogen receptor β actions in the female cardiovascular system: A systematic review of animal and human studies

T Muka, KG Vargas, L Jaspers, K Wen, K Dhana… - Maturitas, 2016 - Elsevier
Five medical databases were searched for studies that assessed the role of ERβ in the
female cardiovascular system and the influence of age and menopause on ERβ functioning …

Sex and haemodynamics in pulmonary arterial hypertension

CE Ventetuolo, A Praestgaard… - European …, 2014 - Eur Respiratory Soc
Female sex is a risk factor for pulmonary arterial hypertension (PAH), yet females have
better survival than males. We sought to determine if sex was associated with baseline …

Common Genetic Variation in the 3′-BCL11B Gene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk: The …

GF Mitchell, GC Verwoert, KV Tarasov… - Circulation …, 2012 - Am Heart Assoc
Background—Carotid-femoral pulse wave velocity (CFPWV) is a heritable measure of aortic
stiffness that is strongly associated with increased risk for major cardiovascular disease …

Association study of the estrogen receptor gene ESR1 with postpartum depression—a pilot study

JK Pinsonneault, D Sullivan, W Sadee… - Archives of women's …, 2013 - Springer
Perinatal mood disorders, such as postpartum depression (PPD), are costly for society, with
potentially serious consequences for mother and child. While multiple genes appear to play …

Individual variation of follicular phase changes in endothelial function across two menstrual cycles

KR Liu, LA Lew, EC McGarity‐Shipley… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? The purpose of this study was to
determine intra‐individual reproducibility of follicular phase changes in endothelial function …

Sex-based differences in vascular function

VM Miller - Women's health, 2010 - journals.sagepub.com
Cardiovascular disease is the leading cause of morbidity and mortality for both men and
women in the USA. However, there are differences between the sexes in age-dependent …

Low expression of ESR1 correlates with ascending aortic dilation and acute type A aortic dissection

Y Zhang, Y Li, S Miao, X Dai, L Chen, L Ma - Gene, 2023 - Elsevier
Background The common genetic signatures of ascending aortic dilation and acute type A
aortic dissection (AAAD) remained unclear. This study aims to investigate the role of ESR1 …

Hypoxia upregulates estrogen receptor β in pulmonary artery endothelial cells in a HIF-1α–dependent manner

AL Frump, M Selej, JA Wood, M Albrecht… - American journal of …, 2018 - atsjournals.org
17β-Estradiol (E2) attenuates hypoxia-induced pulmonary hypertension (HPH) through
estrogen receptor (ER)-dependent effects, including inhibition of hypoxia-induced …

Genetic determinants of arterial stiffness

JG Logan, MB Engler, H Kim - Journal of cardiovascular translational …, 2015 - Springer
Stiffness of large arteries (called arteriosclerosis) is an independent predictor of
cardiovascular morbidity and mortality. Although previous studies have shown that arterial …