Background Long‐acting inhaled ß 2‐adrenergic agonists (LABAs) are recommended as'
add‐on'medication to inhaled corticosteroids (ICS) in the maintenance therapy of asthmatic …

Background Epidemiological evidence has suggested a link between beta‐agonists and
increases in asthma mortality. There has been much debate about possible causal links for …

Background In patients with severe asthma, tiotropium improves lung function and
exacerbation risk when added to high-dose inhaled corticosteroids plus long-acting β 2 …

Summary Background The Single combination budesonide–formoterol inhaler Maintenance
And Reliever Therapy (SMART) regimen reduces severe asthma exacerbations in patients …

Background Recent studies have suggested a possible association between respiratory
infection and the use of inhaled corticosteroids (ICS). We aimed to ascertain the risk of upper …

Purpose This systematic review and meta-analysis was performed to determine the safety of
long-term use of ICS in patients with asthma. Methods A systematic search was made of …

Inhaled corticosteroids are commonly prescribed for patients with severe chronic obstructive
pulmonary disease. Although their use improves quality of life and reduces exacerbations, it …

Background Epidemiological evidence has suggested a link between beta 2‐agonists and
increases in asthma mortality. Much debate has surrounded possible causal links for this …

BACKGROUND: Safety of long-acting beta agonists (LABA) has been questioned and
recent evidence suggested a detrimental effect on asthma control as well as an increased …

Introduction Budesonide-formoterol taken as needed is an emerging treatment for mild
asthma. Objective We used data from the SYGMA studies to assess the safety of As-needed …