11beta-Hydroxysteroid dehydrogenases (11beta-HSDs) interconvert active corticosterone
and inert 11-dehydrocorticosterone. In tissue homogenates, 11beta-HSD type 1 (11beta …

Macrophages exist in almost all animals. In some invertebrates, mesenchymal cells,
endothelial cells or fibroblast‐like cells can transform into macrophages. In vertebrates …

Macrophages are professional phagocytic cells that orchestrate innate immune responses
and have considerable phenotypic diversity at different anatomical locations. However, the …

The renin-angiotensin-aldosterone system controls blood pressure and salt-volume
homeostasis. Renin, which is the first enzymatic step of the cascade, is critically regulated at …

Purpose: Hepatocellular carcinoma is the most common primary malignancy of the liver and
accounts for as many as one million deaths annually worldwide. The present study was …

The goal of this study was to investigate Cystatin SN, a cysteine protease inhibitor, as a
novel tumor marker for colorectal cancer (CRC). Gene expression profiles of mRNA from …

The nuclear receptors liver X receptor alpha (LXRα) and liver X‐receptor beta (LXRβ) have
a well documented role in cholesterol homeostasis and lipid metabolism within tissues and …

Non-specific markers of inflammation such as C-reactive protein (CRP) are associated
statistically with an increased risk of atherosclerosis through mechanisms that have not yet …

Background Liver X receptor (LXR) belongs to the metabolic nuclear receptor superfamily,
which plays a critical regulatory role in vascular physiology/pathology. However, effects of …

Liver X receptors (LXRs) alpha and ss belong to a group of nuclear receptors which, after
ligand binding, regulate gene transcription. Their natural agonists are oxidized cholesterol …