Dosing recommendations for pediatric patients with renal impairment

A Al‐Khouja, K Park, DJC Anderson… - The Journal of …, 2020 - Wiley Online Library
A treatment gap exists for pediatric patients with renal impairment. Alterations in renal
clearance and metabolism of drugs render standard dosage regimens inappropriate and …

Academic cancer center phase i program development

AE Frankel, KT Flaherty, GJ Weiner, R Chen… - The …, 2017 - academic.oup.com
Multiple factors critical to the effectiveness of academic phase I cancer programs were
assessed among 16 academic centers in the US Successful cancer centers were defined as …

A phase I pharmacokinetic and safety study of cabazitaxel in adult cancer patients with normal and impaired renal function

A Azaro, J Rodón, JP Machiels, S Rottey… - Cancer chemotherapy …, 2016 - Springer
Purpose Limited data are available on cabazitaxel pharmacokinetics in patients with renal
impairment. This open-label, multicenter study assessed cabazitaxel in patients with …

[HTML][HTML] Hematologists and nephrologists working together: moving forward with a new integrated care model for blood-related malignancies?

P Niscola, T Caravita, P Tatangelo… - Blood …, 2017 - bloodresearch.or.kr
TO THE EDITOR: Patients with hematological malignancies (HM) are at high risk of renal
complications [1, 2]. Additionally, HM may occur in people with a pre-existing renal …

[PDF][PDF] Dosing oncology therapeutics in combination therapy for renal dysfunction: the University of California San Diego Study of Personalized Cancer Therapy to …

M Nikanjam, J Wing, E Capparelli, R Kurzrock - Cureus, 2018 - cureus.com
Dose reductions are often required to avoid toxicity in combination therapy for advanced
cancers, but information on appropriate dose reductions in renal dysfunction is lacking. This …