Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development

NA Mat Rahim, HY Lee, U Strych… - Human Vaccines & …, 2021 - Taylor & Francis
ABSTRACT In 2017, the World Health Organization (WHO) named A. baumannii as one of
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …

Living with the enemy or uninvited guests: functional genomics approaches to investigating host resistance or tolerance traits to a protozoan parasite, Theileria …

EJ Glass, S Crutchley, K Jensen - Veterinary Immunology and …, 2012 - Elsevier
Many breeds of cattle with long histories of living in areas of endemic disease have evolved
mechanisms that enable them to co-exist with specific pathogens. Understanding the genes …

R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea

O Papapietro, S Teatero, A Thanabalasuriar… - Nature …, 2013 - nature.com
Citrobacter rodentium is a natural mouse pathogen widely used as a model for
enteropathogenic and enterohemorrhagic Escherichia coli infections in humans. While C …

A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage

P Cavailles, P Flori, O Papapietro, C Bisanz… - PLoS …, 2014 - journals.plos.org
Natural immunity or resistance to pathogens most often relies on the genetic make-up of the
host. In a LEW rat model of refractoriness to toxoplasmosis, we previously identified on …

Host Genetic Background Influences the Response to the Opportunistic Pseudomonas aeruginosa Infection Altering Cell-Mediated Immunity and Bacterial …

M De Simone, L Spagnuolo, NI Lorè, G Rossi… - PloS one, 2014 - journals.plos.org
Pseudomonas aeruginosa is a common cause of healthcare-associated infections including
pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of …

Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains

H Hackstein, A Wachtendorf, S Kranz, J Lohmeyer… - Respiratory …, 2012 - Springer
Background Inbred mouse strains are used in different models of respiratory diseases but
the variation of critical respiratory leukocyte subpopulations across different strains is …

Host genetic background impacts modulation of the TLR4 pathway by RON in tissue‐associated macrophages

A Chaudhuri, NS Wilson, B Yang… - Immunology and cell …, 2013 - Wiley Online Library
Toll‐like receptors (TLRs) enable metazoans to mount effective innate immune responses to
microbial and viral pathogens, as well as to endogenous host‐derived ligands. It is …

[HTML][HTML] Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice

T Myers-Morales, KM Bussell, SEF D'Orazio - F1000Research, 2013 - ncbi.nlm.nih.gov
The composition of the intestinal microbiota has wide reaching effects on the health of an
individual, including the development of protective innate immune responses. In this report …

Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice

M De Simone, L Spagnuolo, NI Lorè, C Cigana… - BMC genomics, 2016 - Springer
Background P. aeruginosa is one of the top three causes of opportunistic human bacterial
infections. The remarkable variability in the clinical outcomes of this infection is thought to be …

The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection

L Spagnuolo, M De Simone, NI Lorè, I De Fino… - Scientific reports, 2016 - nature.com
Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes
likely influenced by genetic backgrounds. Here, we investigated the cellular events involved …