Facing the challenges of multidrug-resistant Acinetobacter baumannii: progress and prospects in the vaccine development
ABSTRACT In 2017, the World Health Organization (WHO) named A. baumannii as one of
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …
the three antibiotic-resistant bacterial species on its list of global priority pathogens in dire …
Living with the enemy or uninvited guests: functional genomics approaches to investigating host resistance or tolerance traits to a protozoan parasite, Theileria …
EJ Glass, S Crutchley, K Jensen - Veterinary Immunology and …, 2012 - Elsevier
Many breeds of cattle with long histories of living in areas of endemic disease have evolved
mechanisms that enable them to co-exist with specific pathogens. Understanding the genes …
mechanisms that enable them to co-exist with specific pathogens. Understanding the genes …
R-spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea
O Papapietro, S Teatero, A Thanabalasuriar… - Nature …, 2013 - nature.com
Citrobacter rodentium is a natural mouse pathogen widely used as a model for
enteropathogenic and enterohemorrhagic Escherichia coli infections in humans. While C …
enteropathogenic and enterohemorrhagic Escherichia coli infections in humans. While C …
A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage
P Cavailles, P Flori, O Papapietro, C Bisanz… - PLoS …, 2014 - journals.plos.org
Natural immunity or resistance to pathogens most often relies on the genetic make-up of the
host. In a LEW rat model of refractoriness to toxoplasmosis, we previously identified on …
host. In a LEW rat model of refractoriness to toxoplasmosis, we previously identified on …
Host Genetic Background Influences the Response to the Opportunistic Pseudomonas aeruginosa Infection Altering Cell-Mediated Immunity and Bacterial …
Pseudomonas aeruginosa is a common cause of healthcare-associated infections including
pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of …
pneumonia, bloodstream, urinary tract, and surgical site infections. The clinical outcome of …
Heterogeneity of respiratory dendritic cell subsets and lymphocyte populations in inbred mouse strains
H Hackstein, A Wachtendorf, S Kranz, J Lohmeyer… - Respiratory …, 2012 - Springer
Background Inbred mouse strains are used in different models of respiratory diseases but
the variation of critical respiratory leukocyte subpopulations across different strains is …
the variation of critical respiratory leukocyte subpopulations across different strains is …
Host genetic background impacts modulation of the TLR4 pathway by RON in tissue‐associated macrophages
A Chaudhuri, NS Wilson, B Yang… - Immunology and cell …, 2013 - Wiley Online Library
Toll‐like receptors (TLRs) enable metazoans to mount effective innate immune responses to
microbial and viral pathogens, as well as to endogenous host‐derived ligands. It is …
microbial and viral pathogens, as well as to endogenous host‐derived ligands. It is …
[HTML][HTML] Fecal transplantation does not transfer either susceptibility or resistance to food borne listeriosis in C57BL/6 and BALB/c/By mice
T Myers-Morales, KM Bussell, SEF D'Orazio - F1000Research, 2013 - ncbi.nlm.nih.gov
The composition of the intestinal microbiota has wide reaching effects on the health of an
individual, including the development of protective innate immune responses. In this report …
individual, including the development of protective innate immune responses. In this report …
Mapping genetic determinants of host susceptibility to Pseudomonas aeruginosa lung infection in mice
Background P. aeruginosa is one of the top three causes of opportunistic human bacterial
infections. The remarkable variability in the clinical outcomes of this infection is thought to be …
infections. The remarkable variability in the clinical outcomes of this infection is thought to be …
The host genetic background defines diverse immune-reactivity and susceptibility to chronic Pseudomonas aeruginosa respiratory infection
L Spagnuolo, M De Simone, NI Lorè, I De Fino… - Scientific reports, 2016 - nature.com
Patients with P. aeruginosa airways infection show markedly variable clinical phenotypes
likely influenced by genetic backgrounds. Here, we investigated the cellular events involved …
likely influenced by genetic backgrounds. Here, we investigated the cellular events involved …