Evidence-based review of genomic aberrations in B-lymphoblastic leukemia/lymphoma: Report from the cancer genomics consortium working group for lymphoblastic …

YMN Akkari, H Bruyere, RT Hagelstrom… - Cancer Genetics, 2020 - Elsevier
Clinical management and risk stratification of B-lymphoblastic leukemia/lymphoma (B-
ALL/LBL) depend largely on identification of chromosomal abnormalities obtained using …

IKZF1 Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia

J Paolino, HK Tsai, MH Harris, Y Pikman - Biomedicines, 2024 - mdpi.com
IKZF1 encodes the transcription factor IKAROS, a zinc finger DNA-binding protein with a key
role in lymphoid lineage development. IKAROS plays a critical role in the development of …

Dominant-negative type of IKZF1 deletion showed a favorable prognosis in adult B-cell acute lymphoblastic leukemia

H Kimura, M Onozawa, S Yoshida, N Miyashita… - Annals of …, 2023 - Springer
IKZF1 deletion is a recurrent genomic alteration in B-cell acute lymphoblastic leukemia (B-
ALL) and is divided into dominant-negative (DN) and loss of function (LOF) deletions. The …

Role of Cytogenetics and FISH in Laboratory Workup of B Cell Precursor Acute Lymphoblastic Leukemia

A Dhabe, R Islam, K Ramakrishnan… - Indian Journal of …, 2023 - thieme-connect.com
Modern therapeutic protocols in acute leukemias risk stratify disease based on genetic
characterization of the neoplastic cells and their response to treatment. Genetic …

[PDF][PDF] Functional polymorphism in the 3'UTR of IKZF1 with risk of childhood acute lymphoblastic leukemia in a Chinese population

H Zhang, L Kong - Int J Clin Exp Med, 2019 - e-century.us
IKZF1 is an essential tumor suppressor that regulates the mechanisms of tumorigenesis and
leukemogenesis. IKZF1 polymorphisms have been previously identified with the risk of …

[引用][C] Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic leukemia.

J Hashiguchi, M Onozawa, K Okada… - … Journal of Laboratory …, 2018 - europepmc.org
Quantitative detection of IKZF1 deletion by digital PCR in patients with acute lymphoblastic
leukemia. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …