Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

Freeze tolerance–the ability to survive internal ice formation–has evolved repeatedly in
insects, facilitating survival in environments with low temperatures and/or high risk of …

Gut symbiotic bacteria have a substantial impact on host physiology and ecology. However,
the contribution of gut microbes to host fitness during long-term low-temperature stress is still …

Insects often overcome unfavorable seasons in a hormonally regulated state of diapause
during which their activity ceases, development is arrested, metabolic rate is suppressed …

Temperate, polar and alpine insects generally do not feed over winter and hence must
manage their energy stores to fuel their metabolism over winter and to meet the energetic …

Critical thermal limits often determine species distributions for diverse ectotherms and have
become a useful tool for understanding past and predicting future range shifts in response to …

Cryopreservation has been a key technology in medical science, food preservation, and
many other fields. In a freezing process, the formation of ice crystals may cause significant …

Cryopreservation of red blood cells (RBCs) holds great potential benefits for supplying
transfusion timely in emergencies. Currently, glycerol is the main cryoprotectant permitted in …

Freeze tolerance, the ability to survive internal ice formation, facilitates survival of some
insects in cold habitats. Low-molecular-weight cryoprotectants such as sugars, polyols and …

Nutrients limit production of insects for food and feed: an emphasis on nutritionally essential
amino acids | Animal Frontiers | Oxford Academic Skip to Main Content Advertisement …