Genetic basis of polycystic ovary syndrome (PCOS): current perspectives

MJ Khan, A Ullah, S Basit - The application of clinical genetics, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

Poly cystic ovarian syndrome: an updated overview

S El Hayek, L Bitar, LH Hamdar, FG Mirza… - Frontiers in …, 2016 - frontiersin.org
Poly Cystic Ovarian Syndrome (PCOS) is one of the most common metabolic and
reproductive disorders among women of reproductive age. Women suffering from PCOS …

The role of MiRNA in polycystic ovary syndrome (PCOS)

B Chen, P Xu, J Wang, C Zhang - Gene, 2019 - Elsevier
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in reproductive-aged
women. Clinical manifestations include hyperandrogenism, chronic anovulation, polycystic …

Oxidative stress in granulosa cells contributes to poor oocyte quality and IVF-ET outcomes in women with polycystic ovary syndrome

Q Lai, W Xiang, Q Li, H Zhang, Y Li, G Zhu, C Xiong… - Frontiers of …, 2018 - Springer
The increased levels of intracellular reactive oxygen species (ROS) in granulosa cells (GCs)
may affect the pregnancy results in women with polycystic ovary syndrome (PCOS). In this …

Estradiol signaling at the heart of folliculogenesis: its potential deregulation in human ovarian pathologies

S Chauvin, J Cohen-Tannoudji, CJ Guigon - International journal of …, 2022 - mdpi.com
Estradiol (E2) is a major hormone controlling women fertility, in particular folliculogenesis.
This steroid, which is locally produced by granulosa cells (GC) within ovarian follicles …

Therapeutic role of mesenchymal stem cell-derived extracellular vesicles in female reproductive diseases

Z Liao, C Liu, L Wang, C Sui, H Zhang - Frontiers in endocrinology, 2021 - frontiersin.org
Reproductive disorders, including intrauterine adhesion (IUA), premature ovarian
insufficiency (POI), and polycystic ovary syndrome (PCOS), are great threats to female …

Role of Anti-Müllerian Hormone in pathophysiology, diagnosis and treatment of Polycystic Ovary Syndrome: a review

A Dumont, G Robin, S Catteau-Jonard… - Reproductive Biology …, 2015 - Springer
Polycystic ovary syndrome (PCOS) is the most common cause of chronic anovulation and
hyperandrogenism in young women. Excessive ovarian production of Anti-Müllerian …

Role of anti-Müllerian hormone in the pathogenesis of polycystic ovary syndrome

D Dewailly, AL Barbotin, A Dumont… - Frontiers in …, 2020 - frontiersin.org
Besides its interest for diagnosis, the finding of an elevated serum AMH level in PCOS has
open major pathophysiological issues. This review addresses the three most important …

Evaluation of different ranges of LH: FSH ratios in polycystic ovarian syndrome (PCOS)–Clinical based case control study

NA Malini, KR George - General and comparative endocrinology, 2018 - Elsevier
Background Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine and
metabolic disorder among reproductive aged women, leading to infertility. One of the …

PCOS and role of cumulus gene expression in assessing oocytes quality

N Sayutti, MA Abu, MF Ahmad - Frontiers in Endocrinology, 2022 - frontiersin.org
The global infertility rate has been declining from year to year. PCOS is one of the treatable
accountable causes contributing to anovulatory infertility. Nevertheless, the success rate of …