Effect of different classes of antihypertensive drugs on endothelial function and inflammation

IVG Silva, RC de Figueiredo, DRA Rios - International journal of …, 2019 - mdpi.com
Hypertension is characterized by structural and functional changes in blood vessels that
travel with increased arterial stiffness, vascular inflammation, and endothelial dysfunction …

Role of Oxidative Stress in the Mechanisms of Anthracycline‐Induced Cardiotoxicity: Effects of Preventive Strategies

R Carrasco, RL Castillo, JG Gormaz… - Oxidative medicine …, 2021 - Wiley Online Library
Anthracycline‐induced cardiotoxicity (AIC) persists as a significant cause of morbidity and
mortality in cancer survivors. Although many protective strategies have been evaluated …

Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy

ET van der Westhuizen, B Breton, A Christopoulos… - Molecular …, 2014 - ASPET
The concepts of functional selectivity and ligand bias are becoming increasingly appreciated
in modern drug discovery programs, necessitating more informed approaches to compound …

Therapeutic effect of β-blockers in triple-negative breast cancer postmenopausal women

E Botteri, E Munzone, N Rotmensz, C Cipolla… - Breast cancer research …, 2013 - Springer
Beta-blockers (BB) drugs have been used for decades worldwide, mainly to treat
hypertension. However, in recent epidemiological studies, BBs were suggested to improve …

3D cubic mesoporous silica microsphere as a carrier for poorly soluble drug carvedilol

Y Hu, Z Zhi, Q Zhao, C Wu, P Zhao, H Jiang… - Microporous and …, 2012 - Elsevier
The present work was proposed not only to exploit the potential of 3D cage-like mesoporous
silica SBA-16 with a well-defined spherical morphology as a carrier for poorly soluble drugs …

Risk factors for visual field progression in the low-pressure glaucoma treatment study

CG De Moraes, JM Liebmann, DS Greenfield… - American journal of …, 2012 - Elsevier
PURPOSE: To investigate risk factors associated with visual field progression in the Low-
pressure Glaucoma Treatment Study, a prospective trial designed to compare the effects of …

Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities

N Ramanathan, E Tan, LJ Loh, BS Soh, WN Yap - Nutrition & metabolism, 2018 - Springer
Ageing is a nonmodifiable risk factor that is linked to increased likelihood of cardiovascular
morbidities. Whilst many pharmacological interventions currently exist to treat many of these …

Magnetic solid phase extraction with carbon-coated Fe3O4 nanoparticles coupled to HPLC-UV for the simultaneous determination of losartan, carvedilol, and …

H Heidari, B Limouei-Khosrowshahi - Journal of Chromatography B, 2019 - Elsevier
In this paper, a chemical coprecipitation method was used for the synthesis of Fe 3 O 4
magnetic nanoparticles. The Fe 3 O 4 magnetic nanoparticles were then modified by carbon …

β-Adrenergic blockade in cardiovascular disease

WH Frishman - Journal of cardiovascular pharmacology and …, 2013 - journals.sagepub.com
The development and subsequent clinical application of the β-adrenergic receptor blocking
drugs represent one of the major advances in human pharmacotherapeutics. No other class …

Effect of carvedilol and nebivolol on oxidative stress‐related parameters and endothelial function in patients with essential hypertension

RJ Zepeda, R Castillo, R Rodrigo… - Basic & clinical …, 2012 - Wiley Online Library
Oxidative stress and endothelial dysfunction have been associated with essential
hypertension (EH) mechanisms. The purpose of this study was to evaluate the effect of …