Design and synthesis of novel tetrabromophthalimide derivatives as potential tubulin inhibitors endowed with apoptotic induction for cancer treatment
M Abdel‐Motaal, DA Aldakhili… - Drug Development …, 2024 - Wiley Online Library
Although various approaches exist for treating cancer, chemotherapy continues to hold a
prominent role in the management of this disease. Besides, microtubules serve as a vital …
prominent role in the management of this disease. Besides, microtubules serve as a vital …
Rational Design Problematics of Peptide Nucleic Acids as SARS-CoV-2 Inhibitors
TA Grigoreva, SV Vorona, DS Novikova… - ACS …, 2024 - ACS Publications
The use of viral protein inhibitors has shown to be insufficiently effective in the case of highly
variable SARS-CoV-2. In this work, we examined the possibility of designing agents that …
variable SARS-CoV-2. In this work, we examined the possibility of designing agents that …
LC‐HRMS Profiling and Cytotoxic Potential of Actinomycetes Associated with the Red Sea Soft Coral Sarcophyton glaucum: In vitro and In silico Studies
SS El‐Hawary, MHA Hassan, AO Hudhud… - Chemistry & …, 2024 - Wiley Online Library
In the current study, the actinomycetes associated with the red sea‐derived soft coral
Sarcophyton glaucum were investigated in terms of biological and chemical diversity. Four …
Sarcophyton glaucum were investigated in terms of biological and chemical diversity. Four …
Discovery, synthesis and in silico approach of pyrrolo [3,4-c]pyrroles as SARS-CoV-2 mpro inhibitors
K Saravana Mani, S Rajamanikandan… - Journal of Biomolecular …, 2023 - Taylor & Francis
A new coronavirus has been identified as the contributing agent of the severe acute
respiratory syndrome (SARS). The main viral protease (Mpro), which controls the activities of …
respiratory syndrome (SARS). The main viral protease (Mpro), which controls the activities of …
New Insight into the Anticholinesterase Potential of Cordia dichotoma G. Forst. and Cordia sebestena L. Leaves, Phenolic Characterization of their Active Extracts by …
HM Hussein, E Mohsen, AR Abdelmonem… - Egyptian Journal of …, 2024 - journals.ekb.eg
Alzheimer's disease (AD) is the most prevalent form of dementia with cognitive impairment.
Genus Cordia has been reported in the treatment of neurodegenerative diseases. We aimed …
Genus Cordia has been reported in the treatment of neurodegenerative diseases. We aimed …
[PDF][PDF] Network pharmacology and computational analysis of berberine and kuwanon Z as possible natural antiviral compounds in COVID-19
AVD Ahmad, Q Yasar, SW Khan - Pharmacol Discov, 2024 - tmrjournals.com
Background: Global efforts to discover effective therapeutic agents for combating
coronavirus disease 19 (COVID-19) have intensified the exploration of natural compounds …
coronavirus disease 19 (COVID-19) have intensified the exploration of natural compounds …