Recent advances in targeted delivery of non-coding RNA-based therapeutics for atherosclerosis

X Li, H Qi, W Cui, Z Wang, X Fu, T Li, H Ma, Y Yang… - Molecular Therapy, 2022 - cell.com
Cardiovascular disease (CVD) has overtaken infectious illnesses as the leading cause of
mortality and disability worldwide. The pathology that underpins CVD is atherosclerosis …

High density lipoproteins: metabolism, function, and therapeutic potential

A Jomard, E Osto - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
High Density Lipoproteins (HDLs) have long been considered as “good cholesterol,”
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …

Classification and properties of nanoparticles

S Khan, MK Hossain - Nanoparticle-based polymer composites, 2022 - Elsevier
Being the fundamental component of nanotechnology, nanoparticles have a wide spectrum
of applications in both commercial and domestic aspects. They are being extensively …

Nanoparticle-based drug delivery systems for the treatment of cardiovascular diseases

F Yang, J Xue, G Wang, Q Diao - Frontiers in pharmacology, 2022 - frontiersin.org
Cardiovascular disease is the most common health problem worldwide and remains the
leading cause of morbidity and mortality. Despite recent advances in the management of …

Application of targeted therapy strategies with nanomedicine delivery for atherosclerosis

L Ou, S Zhong, J Ou, J Tian - Acta Pharmacologica Sinica, 2021 - nature.com
Atherosclerosis (AS) is the main pathological cause of coronary heart disease (CHD).
Current clinical interventions including statin drugs can effectively reduce acute myocardial …

Shape matters: morphologically biomimetic particles for improved drug delivery

J Wang, Q Li, J Xue, W Chen, R Zhang… - Chemical Engineering …, 2021 - Elsevier
Natural world provides abundant sources of inspiration for the biomimetic engineering.
Morphology of organisms, as a result of long-term natural selection, can offer particular …

Immunological nanomaterials to combat cancer metastasis

Y Pan, J Cheng, Y Zhu, J Zhang, W Fan… - Chemical Society …, 2024 - pubs.rsc.org
Metastasis causes greater than 90% of cancer-associated deaths, presenting huge
challenges for detection and efficient treatment of cancer due to its high heterogeneity and …

Artificial high‐density lipoprotein‐mimicking nanotherapeutics for the treatment of cardiovascular diseases

H He, K Hong, L Liu… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Despite the ability of current efficacious low‐density lipoprotein‐cholesterol–lowering
therapies to reduce total cardiovascular disease (CVD) risks, CVD still poses major risks for …

Mannose-coated reconstituted lipoprotein nanoparticles for the targeting of tumor-associated macrophages: optimization, characterization, and in vitro evaluation of …

AS Dossou, ME Mantsch, A Kapic, WL Burnett… - Pharmaceutics, 2023 - mdpi.com
Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as
delivery vehicles to a variety of targets, including cancer cells. However, the modification of …

Cholesterol alterations in fragile X syndrome, autism spectrum disorders and other neurodevelopmental disorders.

S Benachenhou, A Laroui, O Dionne… - International Review …, 2023 - europepmc.org
Neurodevelopmental disorders (NDDs) are a group of etiologically diverse diseases
primarily associated with abnormal brain development, impaired cognition, and various …