The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

Although novel therapies, including immunotherapy, have dramatically improved outcomes
for many patients with cancer, overall outcomes are heterogeneous and existing biomarkers …

Altered enteric microorganisms in concert with host genetics shape inflammatory bowel
disease (IBD) phenotypes. However, insight is limited to bacteria and fungi. We found that …

Adenoviral infections continue posing a major threat in severely immunocompromised
patients including particularly allogeneic stem cell transplant recipients. Although …

The intestinal microbiota comprises diverse fungal and viral components, in addition to
bacteria. These microbes interact with the immune system and affect human physiology …

Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

The human body is colonized by a wide range of microorganisms. The field of viromics has
expanded since the first reports on the detection of viruses via metagenomic sequencing in …

Human noroviruses (HuNoVs) are the most common cause of foodborne illness, with a
societal cost of $60 billion and 219,000 deaths/year. The lack of robust small animal models …

Despite improvement in clinical management, allogeneic hematopoietic stem cell
transplantation (HSCT) is still hampered by high morbidity and mortality rates, mainly due to …

Microbiome-derived metabolites influence intestinal homeostasis and regulate graft-versus-
host disease (GVHD), but the molecular mechanisms remain unknown. Here we show the …