Current challenges in the development of vaccines for pneumonic plague
ST Smiley - Expert review of vaccines, 2008 - Taylor & Francis
Inhalation of Yersinia pestis bacilli causes pneumonic plague, a rapidly progressing and
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …
exceptionally virulent disease. Extensively antibiotic-resistant Y. pestis strains exist and we …
Immune defense against pneumonic plague
ST Smiley - Immunological reviews, 2008 - Wiley Online Library
Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …
Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection
T Bergsbaken, MJ Bevan - Nature immunology, 2015 - nature.com
We report that oral infection with Yersinia pseudotuberculosis results in the development of
two distinct populations of pathogen-specific CD8+ tissue-resident memory T cells (TRM …
two distinct populations of pathogen-specific CD8+ tissue-resident memory T cells (TRM …
[PDF][PDF] Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells
G Perona-Wright, K Mohrs, FM Szaba, LW Kummer… - Cell host & …, 2009 - cell.com
Surviving infection represents a balance between the proinflammatory responses needed to
eliminate the pathogen, and anti-inflammatory signals limiting damage to the host. IL-10 is a …
eliminate the pathogen, and anti-inflammatory signals limiting damage to the host. IL-10 is a …
[HTML][HTML] Evaluation of two different vaccine platforms for immunization against melioidosis and glanders
SS Biryukov, CK Cote, CP Klimko… - Frontiers in …, 2022 - frontiersin.org
Burkholderia pseudomallei and the closely related species, Burkholderia mallei, produce
similar multifaceted diseases which range from rapidly fatal to protracted and chronic, and …
similar multifaceted diseases which range from rapidly fatal to protracted and chronic, and …
[HTML][HTML] Mutated and Bacteriophage T4 Nanoparticle Arrayed F1-V Immunogens from Yersinia pestis as Next Generation Plague Vaccines
Pneumonic plague is a highly virulent infectious disease with 100% mortality rate, and its
causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror …
causative organism Yersinia pestis poses a serious threat for deliberate use as a bioterror …
IL-17 contributes to cell-mediated defense against pulmonary Yersinia pestis infection
JS Lin, LW Kummer, FM Szaba… - The Journal of …, 2011 - journals.aai.org
Pneumonic plague is one of the world's most deadly infectious diseases. The causative
bacterium, Yersinia pestis, has the potential to be exploited as a biological weapon, and no …
bacterium, Yersinia pestis, has the potential to be exploited as a biological weapon, and no …
Lung resident memory T cells activated by oral vaccination afford comprehensive protection against pneumonic Yersinia pestis infection
AK Singh, S Majumder, X Wang, R Song… - The Journal of …, 2023 - journals.aai.org
A growing body of evidence has shown that resident memory T (T RM) cells formed in tissue
after mucosal infection or vaccination are crucial for counteracting reinfection by pathogens …
after mucosal infection or vaccination are crucial for counteracting reinfection by pathogens …
Interaction between Yersinia pestis and the Host Immune System
B Li, R Yang - Infection and immunity, 2008 - Am Soc Microbiol
The mammalian immune system comprises multiple physical, chemical, and cellular
components that are traditionally classified as innate and adaptive immunity. The innate …
components that are traditionally classified as innate and adaptive immunity. The innate …
Braun lipoprotein (Lpp) contributes to virulence of yersiniae: potential role of Lpp in inducing bubonic and pneumonic plague
J Sha, SL Agar, WB Baze, JP Olano, AA Fadl… - Infection and …, 2008 - Am Soc Microbiol
Yersinia pestis evolved from Y. pseudotuberculosis to become the causative agent of
bubonic and pneumonic plague. We identified a homolog of the Salmonella enterica serovar …
bubonic and pneumonic plague. We identified a homolog of the Salmonella enterica serovar …