The platelet‑derived growth factor (PDFG) signaling pathway exerts persistent activation in
response to a variety of stimuli and facilitates the progression of hepatic fibrosis. Since this …

Experimental evidence indicates that mesenchymal stromal cells (MSCs) may regulate
tumor microenvironment (TME). It is conceivable that the interaction with MSC can influence …

Objective. We used network pharmacology, molecular docking, and cellular analysis to
explore the pharmacodynamic components and action mechanism of Alpinia officinarum …

The immunotherapeutic approaches based on checkpoint inhibitors, tumor vaccination,
immune cell-based therapy, and cytokines were developed to engage the patient's immune …

A plentiful literature has linked colorectal cancer (CRC) to inflammation and prostaglandin-
endoperoxide synthase (PTGS) 2 expression. Accordingly, several nonsteroidal …

Inflammation plays a central role in prostate cancer (PCa) development through significant
crosstalk between the COX-2-ErbB family receptor network and androgen receptor (AR) …

Mesenchymal stromal cells (MSC) present in the tumor microenvironment [usually named
tumor-associated fibroblasts (TAF)] can exert immunosuppressive effects on T and natural …

TRAF6, a well-known adapter molecule, plays pivotal role in TLR/IL-1R associated signaling
pathway. Although TRAF6 has been shown to have oncogenic activity in various malignant …

STUDY QUESTION Can supplementation of medium with prolactin (PRL), epidermal growth
factor (EGF) and 4-hydroxyestradiol (4-OH-E2) prior to embryo transfer improve implantation …

The biosynthesis of prostanoids is involved in both physiological and pathological
processes. The expression of prostaglandin-endoperoxide synthase 2 (PTGS2; also known …