Wilms tumour

F Spreafico, CV Fernandez, J Brok, K Nakata… - Nature Reviews …, 2021 - nature.com
Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

Cancer in sub-Saharan Africa: a lancet oncology commission

W Ngwa, BW Addai, I Adewole, V Ainsworth… - The Lancet …, 2022 - thelancet.com
Summary In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in
cancer incidence and mortality. Without rapid interventions, data estimates show a major …

Emerging roles of energy metabolism in ferroptosis regulation of tumor cells

X Yao, W Li, D Fang, C Xiao, X Wu, M Li… - Advanced …, 2021 - Wiley Online Library
Ferroptosis is a new form of regulated cell death, which is characterized by the iron‐
dependent accumulation of lethal lipid peroxides and involved in many critical diseases …

Sustainable care for children with cancer: a Lancet Oncology Commission

R Atun, N Bhakta, A Denburg, AL Frazier… - The Lancet …, 2020 - thelancet.com
We estimate that there will be 13· 7 million new cases of childhood cancer globally between
2020 and 2050. At current levels of health system performance (including access and …

The global burden of childhood and adolescent cancer in 2017: an analysis of the Global Burden of Disease Study 2017

LM Force, I Abdollahpour, SM Advani, D Agius… - The Lancet …, 2019 - thelancet.com
Background Accurate childhood cancer burden data are crucial for resource planning and
health policy prioritisation. Model-based estimates are necessary because cancer …

The COVID‐19 pandemic: a rapid global response for children with cancer from SIOP, COG, SIOP‐E, SIOP‐PODC, IPSO, PROS, CCI, and St Jude Global

M Sullivan, E Bouffet… - Pediatric blood & …, 2020 - Wiley Online Library
The COVID‐19 pandemic is one of the most serious global challenges to delivering
affordable and equitable treatment to children with cancer we have witnessed in the last few …

Science and health for all children with cancer

CG Lam, SC Howard, E Bouffet, K Pritchard-Jones - Science, 2019 - science.org
Each year~ 429,000 children and adolescents aged 0 to 19 years are expected to develop
cancer. Five-year survival rates exceed 80% for the 45,000 children with cancer in high …

[HTML][HTML] The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019

EM Alvarez, LM Force, R Xu, K Compton, D Lu… - The Lancet …, 2022 - thelancet.com
Background In estimating the global burden of cancer, adolescents and young adults with
cancer are often overlooked, despite being a distinct subgroup with unique epidemiology …

Childhood cancer: Estimating regional and global incidence

WT Johnston, F Erdmann, R Newton… - Cancer …, 2021 - Elsevier
Background Most of the world's population is not covered by cancer surveillance systems or
vital registration, and worldwide/UN-regional cancer incidence is estimated using a variety …

Lactoferrin: A glycoprotein involved in immunomodulation, anticancer, and antimicrobial processes

Q Rascón-Cruz, EA Espinoza-Sánchez… - Molecules, 2021 - mdpi.com
Lactoferrin is an iron binding glycoprotein with multiple roles in the body. Its participation in
apoptotic processes in cancer cells, its ability to modulate various reactions of the immune …