Trace metals are essential micronutrients required for survival across all kingdoms of life.
From bacteria to animals, metals have critical roles as both structural and catalytic cofactors …

Bacterial infection of implanted scaffolds may have fatal consequences and, in combination
with the emergence of multidrug bacterial resistance, the development of advanced …

Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

Copper dyshomeostasis is associated with a plethora of diseases, supporting the possibility
of applying copper ionophores to regenerate the metal homeostasis and treat copper …

Copper is well known for its antimicrobial and antiviral properties. Under aerobic conditions,
copper toxicity relies in part on the production of reactive oxygen species (ROS), especially …

Highlights•Iron and manganese are withheld from the phagosome to inhibit bacterial
growth.•Excess copper and zinc are used to directly intoxicate intracellular …

Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

Metal ions fulfil a plethora of essential roles within bacterial pathogens. In addition to acting
as necessary cofactors for cellular proteins, making them indispensable for both protein …

As the vanguard against implant-associated infections (IAIs), macrophages facilitate the
phagocytosis and pro-inflammatory polarization of planktonic and biofilm infections, but …

Antibiotic-resistant microbe-mediated deaths are a major worldwide health issue.
Unfortunately, due to microbial adaptation to develop resistance, some antibiotics are …