Ameliorative effects of gut microbial metabolite urolithin a on pancreatic diseases

K Li, Y Xiao, J Bian, L Han, C He, E El-Omar, L Gong… - Nutrients, 2022 - mdpi.com
Urolithin A (Uro A) is a dietary metabolite of the intestinal microbiota following the ingestion
of plant-based food ingredients ellagitannins and ellagic acid in mammals. Accumulating …

Acute and chronic pancreatitis disease prevalence, classification, and comorbidities: a cohort study of the UK BioBank

DM Spagnolo, PJ Greer, CS Ohlsen… - Clinical and …, 2022 - journals.lww.com
METHODS: A pancreatitis cohort of more than 4,200 patients and 24,000 controls were
identified in the UK BioBank (UKBB) consortium. A descriptive analysis was completed …

Chronic pancreatitis and cancer risk in a matched cohort study using national claims data in South Korea

M Han, TPT Tran, JK Oh - Scientific Reports, 2022 - nature.com
This study aimed to examine the association between chronic pancreatitis (CP) and cancer
incidence and mortality among the Korean population. Based on a cancer-free cohort of …

[HTML][HTML] Assessment of pain associated with chronic pancreatitis: An international consensus guideline

AM Drewes, CL van Veldhuisen, MD Bellin… - Pancreatology, 2021 - Elsevier
Pain is the most common symptom in chronic pancreatitis (CP) with a major impact on
quality of life. Few validated questionnaires to assess pain in CP exist, and the lack of …

Catechin hydrate ameliorates cerulein‑induced chronic pancreatitis via the inactivation of TGF‑β/Smad2 signaling

B Kweon, DU Kim, JY Oh… - Molecular Medicine …, 2023 - spandidos-publications.com
Chronic pancreatitis (CP) is a pancreatic inflammatory disease associated with histological
changes, including fibrosis, acinar cell loss and immune cell infiltration, and leads to …

[HTML][HTML] Incidence, prevalence, and comorbidities of chronic pancreatitis: A 7-year population-based study

QY Cai, K Tan, XL Zhang, X Han, JP Pan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Chronic pancreatitis (CP) is a fibroinflammatory syndrome leading to
reduced quality of life and shortened life expectancy. Population-based estimates of the …

Metformin treatment is associated with reduced risk of hypoglycaemia, major adverse cardiovascular events, and all-cause mortality in patients with post-pancreatitis …

L Davidsen, MH Jensen, ME Cook… - European Journal of …, 2024 - academic.oup.com
Objective Post-pancreatitis diabetes mellitus (PPDM) is a frequent complication of
pancreatitis and is associated with an increased risk of adverse outcomes. Metformin is …

Disorders of the Pancreas

JC McDougal, ND Dharmadhikari… - Primary Care: Clinics …, 2023 - primarycare.theclinics.com
The pancreas is an essential organ which lies across the posterior abdominal wall between
the duodenum and spleen. Owing to its dual exocrine and endocrine function, it plays a vital …

Glucose-lowering therapy in patients with postpancreatitis diabetes mellitus: a nationwide population-based cohort study

R Viggers, MH Jensen, HVB Laursen… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Postpancreatitis diabetes mellitus (PPDM) is a type of secondary diabetes that
requires special considerations for management. The main objective was to examine …

High-mobility group box 1 fragment ameliorates chronic pancreatitis induced by caerulein in mice

D Hokkoku, K Sasaki, S Kobayashi, T Shimbo… - Journal of …, 2024 - Springer
Background Chronic pancreatitis (CP) is a progressive disease characterized by pancreatic
fibrosis for which effective treatment options are lacking. Mesenchymal stem cells (MSCs) …