Immunopeptides: immunomodulatory strategies and prospects for ocular immunity applications

Y Tang, S Qu, Z Ning, H Wu - Frontiers in Immunology, 2024 - frontiersin.org
Immunopeptides have low toxicity, low immunogenicity and targeting, and broad application
prospects in drug delivery and assembly, which are diverse in application strategies and …

Dendritic cell hybrid nanovaccine for mild heat inspired cancer immunotherapy

C Shi, C Jian, L Wang, C Gao, T Yang, Z Fu… - Journal of …, 2023 - Springer
Cancer therapeutic vaccine can induce antigen-specific immune response, which has
shown great potential in cancer immunotherapy. As the key factor of vaccine, antigen plays a …

COVID-19 Variants and Vaccine Development

Z Zhao, S Bashiri, ZM Ziora, I Toth, M Skwarczynski - Viruses, 2024 - mdpi.com
Coronavirus disease 2019 (COVID-19), the global pandemic caused by severe acute
respiratory syndrome 2 virus (SARS-CoV-2) infection, has caused millions of infections and …

[HTML][HTML] Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer

FZ Firdaus, S Bartlett, WM Hussein, L Lu, Q Wright… - Pharmaceutics, 2023 - mdpi.com
Human papilloma virus (HPV) is responsible for all cases of cervical cancer. While
prophylactic vaccines are available, the development of peptide-based vaccines as a …

In silico design and immunoinformatics analysis of a chimeric vaccine construct based on Salmonella pathogenesis factors

MHJN Abadi, FA Abyaneh, N Zare, J Zamani… - Microbial …, 2023 - Elsevier
Currently, there are two vaccines based on killed and/or weakened Salmonella bacteria, but
no recombinant vaccine is available for preventing or treating the disease. We used an in …

Protective Efficacy Induced by the Common Eimeria Antigen Elongation Factor 2 against Challenge with Three Eimeria Species in Chickens

Y Mi, W Ding, L Xu, M Lu, R Yan, X Li, X Song - Vaccines, 2023 - mdpi.com
Avian coccidiosis arises from co-infection involving multiple Eimeria species, which could
give rise to substantial economic losses in the global poultry industry. As a result, multivalent …

Transdermal microneedles integrating biomimetic self-adjuvant particles for enhanced immunity

M Jiang, Y Zhang, T Zheng, Y Chang, N Qiao, M Qin… - Nano Today, 2024 - Elsevier
Optimal exposure and interaction of subunit antigens with the immune system are crucial for
effective immunity. The epidermis and dermis, which harbor a significant population of …

The development of surface-modified liposomes as an intranasal delivery system for group a Streptococcus vaccines

J Yang, JC Boer, M Khongkow, S Phunpee, ZG Khalil… - Vaccines, 2023 - mdpi.com
Intranasal vaccine administration can overcome the disadvantages of injectable vaccines
and present greater efficiency for mass immunization. However, the development of …

Spatiotemporal coordination of antigen presentation and co-stimulatory signal for enhanced anti-tumor vaccination

S Peng, Y Yan, K Ogino, G Ma, Y Xia - Journal of Controlled Release, 2024 - Elsevier
Controlled-release systems enhance anti-tumor effects by leveraging local antigen
persistence for antigen-presenting cells (APCs) recruitment and T cell engagement …

[HTML][HTML] Cholesterol as an inbuilt immunoadjuvant for a lipopeptide vaccine against group A Streptococcus infection

N Alharbi, AO Shalash, P Koirala, JC Boer… - Journal of Colloid and …, 2024 - Elsevier
Peptide-based vaccines can trigger highly specific immune responses, although peptides
alone are usually unable to confer strong humoral or cellular immunity. Consequently …