Hemophilia A and B are rare X‐linked inherited bleeding disorders caused by complete or
partial deficiency in or the absence of coagulation factors VIII and IX. Recurrent joint …

Platelets play a major role in hemostasis as ppwell as in many other physiological and
pathological processes. Accordingly, production of about 1011 platelet per day as well as …

Methods for the analysis of cell secretions at the single-cell level only provide
semiquantitative endpoint readouts. Here we describe a microwell array for the real-time …

Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …

The Warburg effect is a significant hallmark of gastric cancer (GC), and increasing evidence
emphasizes the crucial role of circular RNAs (circRNAs) in GC tumorigenesis. However, the …

Hemophilia A and hemophilia B are rare congenital, recessive X-linked disorders caused by
lack or deficiency of clotting factor VIII (FVIII) or IX (FIX), respectively. The severity of the …

The implementation of high‐throughput sequencing (HTS) technologies in research and
diagnostic laboratories has linked many new genes to rare bleeding, thrombotic, and …

Abstract Background Inherited platelet disorders (IPDs) are rare diseases characterized by
reduced blood platelet counts and/or impaired platelet function. Recognizing IPDs is …

In the last decade, improvements in genetic testing have revolutionized the molecular
diagnosis of inherited thrombocytopenias (ITs), increasing the spectrum of knowledge of …

Molecular diagnostics of inherited platelet disorders (IPD) has been revolutionized by the
implementation of high‐throughput sequencing (HTS) approaches. A conclusive diagnosis …