Human exposure to a wide range of chemical compounds, some of which pose significant
health risks, underscores the critical need to assess chemical toxicity comprehensively …

Platelets are anucleate cell fragments released from megakaryocytes, their precursor cells
which reside within the bone marrow. Platelets participate in a wide variety of processes like …

Hemostasis is a complex and tightly regulated system that attempts to maintain a
homeostatic balance to permit normal blood flow, without bleeding or thrombosis …

Zaburzenia funkcji płytek krwi (PFD) to rzadko występująca, a zarazem heterogenna grupa
chorób należących do skaz krwotocznych. Kompleksowa diagnostyka nieprawidłowej …

As disfunções plaquetares hereditárias (DPH) constituem um grupo heterogéneo de
patologias raras, subdiagnosticadas que afetam o número de plaquetas (trombocitopenia) …

Method Approximately, 7500 index patients (IPs) with known deficiencies in one or more
than one coagulation factors have been screened by Sanger Sequencing and Multiplex …

Abstract The implementation of High Throughput Sequencing (HTS) technologies in
research and diagnostic laboratories has linked many new genes to rare bleeding …

Method Clinical assessment, platelet phenotyping by flow-cytometry, immunofluorescence
microscopy, standard aggregometry, DNA analysis as well as a platelet reactive antibody …