There are many pathways of endocytosis at the cell surface that apparently operate at the
same time. With the advent of new molecular genetic and imaging tools, an understanding of …

Although viruses are simple in structure and composition, their interactions with host cells
are complex. Merely to gain entry, animal viruses make use of a repertoire of cellular …

Endocytosis occurs at the cell surface and involves internalization of the plasma membrane
(PM) along with its constituent membrane proteins and lipids. Endocytosis is involved in …

Membrane lipids and proteins are non-randomly distributed and are unable to diffuse freely
in the plane of the membrane. This is because of multiple constraints imposed both by the …

The elegant icosahedral surface of the papillomavirus virion is formed by a single protein
called L1. Recombinant L1 proteins can spontaneously self-assemble into a highly …

HPVs (human papillomaviruses) and other papillomaviruses have a unique mechanism of
infection that has likely evolved to limit infection to the basal cells of stratified epithelium, the …

Infectious endocytosis of incoming human papillomavirus type 16 (HPV-16), the main
etiological agent of cervical cancer, is poorly characterized in terms of cellular requirements …

The mammalian target of rapamycin (mTOR) downstream of phosphatidylinositol 3-kinase
(PI3K) in the growth factor receptor (GFR) pathway is a crucial metabolic sensor that …

As the primary etiological agents of cervical cancer, human papillomaviruses (HPVs) must
deliver their genetic material into the nucleus of the target cell. The viral capsid has evolved …

Human papillomaviruses (HPVs) infect epithelia and can lead to the development of lesions,
some of which have malignant potential. HPV type 16 (HPV16) is the most oncogenic …