Tetraspanin proteins promote multiple cancer stages
ME Hemler - Nature Reviews Cancer, 2014 - nature.com
An abundance of evidence shows supporting roles for tetraspanin proteins in human cancer.
Many studies show that the expression of tetraspanins correlates with tumour stage, tumour …
Many studies show that the expression of tetraspanins correlates with tumour stage, tumour …
Tetraspanins as regulators of the tumour microenvironment: implications for metastasis and therapeutic strategies
S Detchokul, ED Williams, MW Parker… - British journal of …, 2014 - Wiley Online Library
One of the hallmarks of cancer is the ability to activate invasion and metastasis. Cancer
morbidity and mortality are largely related to the spread of the primary, localized tumour to …
morbidity and mortality are largely related to the spread of the primary, localized tumour to …
CD9 mediates the uptake of extracellular vesicles from cancer-associated fibroblasts that promote pancreatic cancer cell aggressiveness
In pancreatic ductal adenocarcinoma (PDAC), signaling from stromal cells is implicated in
metastatic progression. Tumor-stroma cross-talk is often mediated through extracellular …
metastatic progression. Tumor-stroma cross-talk is often mediated through extracellular …
Prognostic value and multifaceted roles of tetraspanin CD9 in cancer
R Ondruššek, B Kvokačková, K Kryštofová… - Frontiers in …, 2023 - frontiersin.org
CD9 is a crucial regulator of cell adhesion in the immune system and plays important
physiological roles in hematopoiesis, blood coagulation or viral and bacterial infections. It is …
physiological roles in hematopoiesis, blood coagulation or viral and bacterial infections. It is …
Tetraspanins in human epithelial malignancies
HM Romanska, F Berditchevski - The Journal of Pathology, 2011 - Wiley Online Library
Transmembrane proteins of the tetraspanin superfamily are implicated in a broad spectrum
of cellular processes in many biological systems in both health and disease. Tetraspanins …
of cellular processes in many biological systems in both health and disease. Tetraspanins …
Tetraspanins and tumor progression
MM Richardson, LK Jennings, XA Zhang - Clinical & experimental …, 2011 - Springer
Transmembrane protein tetraspanins either promote or suppress tumor invasion and
metastasis. Their effects on tumor progression depend on the multimolecular …
metastasis. Their effects on tumor progression depend on the multimolecular …
TSPAN8 as a novel emerging therapeutic target in cancer for monoclonal antibody therapy
K Heo, S Lee - Biomolecules, 2020 - mdpi.com
Tetraspanin 8 (TSPAN8) is a member of the tetraspanin superfamily that forms TSPAN8-
mediated protein complexes by interacting with themselves and other various cellular …
mediated protein complexes by interacting with themselves and other various cellular …
Laparoscopic total gastrectomy as a valid procedure to treat gastric cancer option both in early and advanced stage: A systematic review and meta-analysis
Although laparoscopic total gastrectomy (LTG) compared to open total gastrectomy (OTG)
has been widely used for advanced gastric cancer patients, its oncologic validity is yet to be …
has been widely used for advanced gastric cancer patients, its oncologic validity is yet to be …
Identification of cluster of differentiation molecule-associated microRNAs as potential therapeutic targets for gastrointestinal cancer immunotherapy
H Zhang, M Li, PJ Kaboli, H Ji, F Du… - … journal of biological …, 2021 - journals.sagepub.com
Background: Cluster of differentiation molecules are markers of immune cells that have been
identified as a potential immunotherapeutic target for cancer treatment. MicroRNAs are small …
identified as a potential immunotherapeutic target for cancer treatment. MicroRNAs are small …
[HTML][HTML] Tetraspanins: Spanning from solid tumors to hematologic malignancies
YG Yang, IN Sari, MF Zia, SR Lee, SJ Song… - Experimental …, 2016 - Elsevier
Highlights•Tetraspanins are expressed in solid tumors and hematologic malignancies.•
Tetraspanin 3 has a critical role in myeloid leukemia.•Tetraspanin 3 is a potential target of …
Tetraspanin 3 has a critical role in myeloid leukemia.•Tetraspanin 3 is a potential target of …