Towards population-scale long-read sequencing
W De Coster, MH Weissensteiner… - Nature Reviews …, 2021 - nature.com
Long-read sequencing technologies have now reached a level of accuracy and yield that
allows their application to variant detection at a scale of tens to thousands of samples …
allows their application to variant detection at a scale of tens to thousands of samples …
The integrated genomics of crop domestication and breeding
X Huang, S Huang, B Han, J Li - Cell, 2022 - cell.com
As a major event in human civilization, wild plants were successfully domesticated to be
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …
crops, largely owing to continuing artificial selection. Here, we summarize new discoveries …
Graph pangenome captures missing heritability and empowers tomato breeding
Missing heritability in genome-wide association studies defines a major problem in genetic
analyses of complex biological traits,. The solution to this problem is to identify all causal …
analyses of complex biological traits,. The solution to this problem is to identify all causal …
Genome evolution and diversity of wild and cultivated potatoes
Potato (Solanum tuberosum L.) is the world's most important non-cereal food crop, and the
vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances …
vast majority of commercially grown cultivars are highly heterozygous tetraploids. Advances …
Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species
Effective utilization of wild relatives is key to overcoming challenges in genetic improvement
of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …
of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …
Detection of mosaic and population-level structural variants with Sniffles2
Calling structural variations (SVs) is technically challenging, but using long reads remains
the most accurate way to identify complex genomic alterations. Here we present Sniffles2 …
the most accurate way to identify complex genomic alterations. Here we present Sniffles2 …
Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing
Advancing crop genomics requires efficient genetic systems enabled by high-quality
personalized genome assemblies. Here, we introduce RagTag, a toolset for automating …
personalized genome assemblies. Here, we introduce RagTag, a toolset for automating …
Pangenomic analysis identifies structural variation associated with heat tolerance in pearl millet
Pearl millet is an important cereal crop worldwide and shows superior heat tolerance. Here,
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
we developed a graph-based pan-genome by assembling ten chromosomal genomes with …
A graph-based genome and pan-genome variation of the model plant Setaria
Setaria italica (foxtail millet), a founder crop of East Asian agriculture, is a model plant for C4
photosynthesis and developing approaches to adaptive breeding across multiple climates …
photosynthesis and developing approaches to adaptive breeding across multiple climates …
Pan-genome analysis of 33 genetically diverse rice accessions reveals hidden genomic variations
P Qin, H Lu, H Du, H Wang, W Chen, Z Chen, Q He… - Cell, 2021 - cell.com
Structural variations (SVs) and gene copy number variations (gCNVs) have contributed to
crop evolution, domestication, and improvement. Here, we assembled 31 high-quality …
crop evolution, domestication, and improvement. Here, we assembled 31 high-quality …