The tobacco smoke component, acrolein, as a major culprit in lung diseases and respiratory cancers: Molecular mechanisms of acrolein cytotoxic activity

P Hikisz, D Jacenik - Cells, 2023 - mdpi.com
Acrolein, a highly reactive unsaturated aldehyde, is a ubiquitous environmental pollutant
that seriously threatens human health and life. Due to its high reactivity, cytotoxicity and …

Dysregulation of immunity by cigarette smoking promotes inflammation and cancer: a review

Y Liu, L Lu, H Yang, X Wu, X Luo, J Shen, Z Xiao… - Environmental …, 2023 - Elsevier
Smoking is a serious global health issue. Cigarette smoking contains over 7000 different
chemicals. The main harmful components include nicotine, acrolein, aromatic hydrocarbons …

Impact of Electronic Cigarettes, Heated Tobacco Products and Conventional Cigarettes on the Generation of Oxidative Stress and Genetic and Epigenetic Lesions in …

G Zarcone, M Lenski, T Martinez, S Talahari, O Simonin… - Toxics, 2023 - mdpi.com
Electronic cigarettes (e-cig) and heated tobacco products (HTP) are often used as smoking
cessation aids, while the harm reduction effects of these alternatives to cigarettes are still the …

Interaction between cigarette smoke and human papillomavirus 16 E6/E7 oncoproteins to induce SOD2 expression and DNA damage in head and neck cancer

D Carrillo-Beltrán, JC Osorio, R Blanco, C Oliva… - International Journal of …, 2023 - mdpi.com
Even though epidemiological studies suggest that tobacco smoking and high-risk human
papillomavirus (HR-HPV) infection are mutually exclusive risk factors for developing head …

[HTML][HTML] Maternal smoking in the first trimester and its consequence on the early placenta

D Hoch, A Majali-Martinez, EE Bankoglu… - Laboratory …, 2023 - Elsevier
Smoking during pregnancy increases the risk of adverse pregnancy outcomes, such as
stillbirth and fetal growth restriction. This suggests impaired placental function and restricted …

Comparative analyses of transcriptome sequencing and carcinogenic exposure toxicity of nicotine and 6-methyl nicotine in human bronchial epithelial cells

H Qi, X Chang, K Wang, Q Xu, M Liu, B Han - Toxicology in Vitro, 2023 - Elsevier
Electronic cigarettes have become a purported safer alternative to the conventional
cigarettes in recent years. Nicotine is the main component of electronic cigarettes, and other …

Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex

F Vivarelli, C Morosini, L Rullo, LM Losapio… - Frontiers in …, 2024 - frontiersin.org
Although the Food and Drug Administration has authorized the marketing of “heat-not-
burn”(HnB) electronic cigarettes as a modified risk tobacco product (MRTP), toxicological …

Expression deregulation of genes related to DNA repair and lead toxicity in occupationally exposed industrial workers

Z Akram, I Mahjabeen, M Batool, S Kanwal… - International archives of …, 2023 - Springer
Objective Globally millions of people working in various industries and are exposed to
different toxins which may affect their genetic stability and DNA integrity. Present study was …

Impact of e‐cigarette liquid on porcine lung tissue—Ex vivo confocal Raman micro‐spectroscopy study

A Jaafar, A Albarazanchi, MJ Kadhim… - Journal of …, 2023 - Wiley Online Library
Ex vivo porcine lung immersed in e‐liquid was investigated in‐depth using confocal Raman
micro‐spectroscopy to assess the e‐liquid influence on the lung. It was found that lung …

Fruit flavors in electronic cigarettes (ECIGs) are associated with nocturnal dry cough: A population longitudinal analysis

Z Quinones Tavarez, DP Croft, D Li, SR Gill… - Plos one, 2024 - journals.plos.org
Evidence from in vitro and animal models has identified the pulmonary toxicity of flavors in
electronic cigarettes (ECIGs); however, less is known from epidemiological studies about the …