[HTML][HTML] DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer

D Müller, B Győrffy - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Role of the gut microbiota and its metabolites in tumorigenesis or development of colorectal cancer

R Qu, Y Zhang, Y Ma, X Zhou, L Sun, C Jiang… - Advanced …, 2023 - Wiley Online Library
Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives

J Ibrahim, M Peeters, G Van Camp… - European Journal of …, 2023 - Elsevier
The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

Colon cancer transcriptome

K Mokhtari, M Peymani, M Rashidi… - Progress in biophysics …, 2023 - Elsevier
Over the last four decades, methodological innovations have continuously changed
transcriptome profiling. It is now feasible to sequence and quantify the transcriptional outputs …

Untargeted GC-MS-based metabolomics for early detection of colorectal cancer

G Zhu, Y Wang, W Wang, F Shang, B Pei… - Frontiers in …, 2021 - frontiersin.org
Background Colorectal cancer (CRC) is one of the most common malignant gastrointestinal
cancers in the world with a 5-year survival rate of approximately 68%. Although researchers …

Promising epigenetic biomarkers for the early detection of colorectal cancer: a systematic review

SA Anghel, CB Ioniță-Mîndrican, I Luca, AL Pop - Cancers, 2021 - mdpi.com
Simple Summary High-performance, non-invasive screening is a requirement in colorectal
cancer (CRC) as early detection is a key in reducing disease-related mortality in CRC …

Genomic and transcriptomic research in the discovery and application of colorectal cancer circulating markers

AA Ponomaryova, EY Rykova, AI Solovyova… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is the most frequently occurring malignancy in the world. However,
the mortality from CRC can be reduced through early diagnostics, selection of the most …

Epigenetic regulation of major histocompatibility complexes in gastrointestinal malignancies and the potential for clinical interception

JE Tovar Perez, S Zhang, W Hodgeman, S Kapoor… - Clinical …, 2024 - Springer
Background Gastrointestinal malignancies encompass a diverse group of cancers that pose
significant challenges to global health. The major histocompatibility complex (MHC) plays a …

Diagnosis of pulmonary nodules by DNA methylation analysis in bronchoalveolar lavage fluids

L Li, Z Ye, S Yang, H Yang, J Jin, Y Zhu, J Tao… - Clinical …, 2021 - Springer
Background Lung cancer is the leading cause of cancer-related mortality. The alteration of
DNA methylation plays a major role in the development of lung cancer. Methylation …

Updates of liquid biopsy in oral cancer and multiomics analysis

X Zhang, B Li - Oral Diseases, 2023 - Wiley Online Library
Liquid biopsy is a method sampled from body fluids, such as blood, saliva, urine, pleural
effusion, cerebrospinal fluid, and so on. It is minimally invasive and reproducible and …