[HTML][HTML] Ex-vivo Kidney Machine Perfusion: Therapeutic Potential

R Zulpaite, P Miknevicius, B Leber, K Strupas… - Frontiers in …, 2021 - frontiersin.org
Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

The future of organ perfusion and re‐conditioning

A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …

[HTML][HTML] Twenty-four–hour normothermic perfusion of discarded human kidneys with urine recirculation

A Weissenbacher, LL Faro, O Boubriak… - American Journal of …, 2019 - Elsevier
Transportable normothermic kidney perfusion for 24 hours or longer could enable viability
assessment of marginal grafts, increased organ use, and improved transplant logistics …

[HTML][HTML] Normothermic ex vivo kidney perfusion for human kidney transplantation: first North American results

LI Mazilescu, P Urbanellis, SJ Kim, T Goto… - …, 2022 - journals.lww.com
Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

Normothermic ex vivo kidney perfusion improves early DCD graft function compared with hypothermic machine perfusion and static cold storage

P Urbanellis, M Hamar, JM Kaths, D Kollmann… - …, 2020 - journals.lww.com
Background. Better preservation strategies for the storage of donation after circulatory death
grafts are essential to improve graft function and to increase the kidney donor pool. We …

[HTML][HTML] Continuous normothermic ex vivo kidney perfusion is superior to brief normothermic perfusion following static cold storage in donation after circulatory death …

JM Kaths, JY Cen, YM Chun, J Echeverri… - American Journal of …, 2017 - Elsevier
Hypothermic preservation is known to cause renal graft injury, especially in donation after
circulatory death (DCD) kidney transplantation. We investigated the impact of cold storage …

[HTML][HTML] Renal normothermic machine perfusion: the road toward clinical implementation of a promising pretransplant organ assessment tool

TL Hamelink, B Ogurlu, J De Beule, VA Lantinga… - …, 2022 - journals.lww.com
The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …

[HTML][HTML] A machine-learning approach to human ex vivo lung perfusion predicts transplantation outcomes and promotes organ utilization

AT Sage, LL Donahoe, AA Shamandy… - Nature …, 2023 - nature.com
Ex vivo lung perfusion (EVLP) is a data-intensive platform used for the assessment of
isolated lungs outside the body for transplantation; however, the integration of artificial …

[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation

JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …

[HTML][HTML] Synthetic hemoglobin-based oxygen carriers are an acceptable alternative for packed red blood cells in normothermic kidney perfusion

MM Aburawi, FM Fontan, N Karimian, C Eymard… - American Journal of …, 2019 - Elsevier
Normothermic machine perfusion presents a novel platform for pretransplant assessment
and reconditioning of kidney grafts. Maintaining the metabolic activity of a preserved graft at …