Extracellular matrix stiffness—The central cue for skin fibrosis

K Wang, D Wen, X Xu, R Zhao, F Jiang… - Frontiers in Molecular …, 2023 - frontiersin.org
Skin fibrosis is a physiopathological process featuring the excessive deposition of
extracellular matrix (ECM), which is the main architecture that provides structural support …

Complex interactions of cellular players in chronic Graft-versus-Host Disease

LM Gail, KJ Schell, P Łacina, J Strobl… - Frontiers in …, 2023 - frontiersin.org
Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects
many patients after allogeneic hematopoietic stem cell transplantation. Although we have …

A novel pyroptosis-related LncRNA signature predicts prognosis and indicates tumor immune microenvironment in skin cutaneous melanoma

Z Wang, AH Hounye, J Liu, J Zhang, M Qi - Life Sciences, 2022 - Elsevier
Aims To explore the correlation between the pyroptosis-related lncRNAs (PRlncRNAs) and
the prognosis of skin cutaneous melanoma (SKCM), and clarify the effects of the PRlncRNAs …

[HTML][HTML] Bioinformatics analysis and experimental validation of a novel autophagy-related signature relevant to immune infiltration for recurrence prediction after …

H Wang, C Yang, D Li, R Wang, Y Li, L Lv - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) remains imposing an enormous economic and healthcare
burden worldwide. In this present study, we constructed and validated a novel autophagy …

The IFN-γ-related long non-coding RNA signature predicts prognosis and indicates immune microenvironment infiltration in uterine corpus endometrial carcinoma

C Gu, C Lin, Z Zhu, L Hu, F Wang, X Wang… - Frontiers in …, 2022 - frontiersin.org
Background One of the most common diseases that have a negative impact on women's
health is endometrial carcinoma (EC). Advanced endometrial cancer has a dismal prognosis …

Weighted gene co‐expression network analysis and machine learning identified the lipid metabolism‐related gene LGMN as a novel biomarker for keloid

Q Wang, X Huang, S Zeng, R Zhou… - Experimental …, 2024 - Wiley Online Library
The aetiology of keloid formation remains unclear, and existing treatment modalities have
not definitively established a successful approach. Therefore, it is necessary to identify …

Identification and preliminary validation of synovial tissue-specific genes and their-mediated biological mechanisms in rheumatoid arthritis

Y Liu, J Wang, X Li, H Chen, Q Xia, J Li - International …, 2023 - Elsevier
Background Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease. It is
well known that the formation of positive feedback between synovial hyperplasia and …

[HTML][HTML] Clinical significance for diagnosis and prognosis of POP1 and its potential role in breast cancer: a comprehensive analysis based on multiple databases

X He, J Wang, H Yu, W Lv, Y Wang, Q Zhang… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Background: Breast cancer (BC) is one of the most common cancers in women. The
discovery of available biomarkers is crucial for early diagnosis and improving prognosis …

Noncoding-RNA mediated high expression of zinc finger protein 268 suppresses clear cell renal cell carcinoma progression by promoting apoptosis and regulating …

K Wang, Y Gu, J Ni, H Zhang, Y Wang, Y Zhang… - …, 2022 - Taylor & Francis
Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant kidney tumors
with a poor prognosis. Accumulating evidence proves that zinc finger protein 268 (ZNF268) …

[HTML][HTML] A pan-cancer analysis of the oncogenic role of ribonucleotide reductase subunit M2 in human tumors

Y Li, W Fu, Z Geng, Y Song, X Yang, T He, J Wu… - PeerJ, 2022 - peerj.com
Background Recent studies have identified ribonucleotide reductase subunit M2 (RRM2) as
a putative promoter of tumors. However, no systematic analysis of its carcinogenicity has …