Anti‐ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery

CY Shen, JG Jiang, L Yang… - British Journal of …, 2017 - Wiley Online Library
Ageing, an unanswered question in the medical field, is a multifactorial process that results
in a progressive functional decline in cells, tissues and organisms. Although it is impossible …

Anti-senescence compounds: a potential nutraceutical approach to healthy aging

F Gurău, S Baldoni, F Prattichizzo, E Espinosa… - Ageing Research …, 2018 - Elsevier
The desire of eternal youth seems to be as old as mankind. However, the increasing life
expectancy experienced by populations in developed countries also involves a significantly …

[HTML][HTML] Molecular chaperones and proteostasis regulation during redox imbalance

K Niforou, C Cheimonidou, IP Trougakos - Redox biology, 2014 - Elsevier
Free radicals originate from both exogenous environmental sources and as by-products of
the respiratory chain and cellular oxygen metabolism. Sustained accumulation of free …

Curcumin as prospective anti-aging natural compound: focus on brain

T Benameur, R Soleti, MA Panaro, ME La Torre… - Molecules, 2021 - mdpi.com
The nutrients and their potential benefits are a new field of study in modern medicine for
their positive impact on health. Curcumin, the yellow polyphenolic compound extracted from …

C2C12 cell model: its role in understanding of insulin resistance at the molecular level and pharmaceutical development at the preclinical stage

CY Wong, H Al-Salami, CR Dass - Journal of Pharmacy and …, 2020 - academic.oup.com
Objectives The myoblast cell line, C2C12, has been utilised extensively in vitro as an
examination model in understanding metabolic disease progression. Although it is …

Edible flowers as functional raw materials: A review on anti-aging properties

Q Chen, B Xu, W Huang, AT Amrouche… - Trends in Food Science …, 2020 - Elsevier
Background Diet is a major determinant of aging and lifespan. Development and utilization
of food resources with potential anti-aging activity have attracted increasing attention from …

[HTML][HTML] Aging is not a disease: implications for intervention

SIS Rattan - Aging and disease, 2014 - ncbi.nlm.nih.gov
Aging of biological systems occurs in spite of numerous complex pathways of maintenance,
repair and defense. There are no gerontogenes which have the specific evolutionary …

Taxifolin retards the D-galactose-induced aging process through inhibiting Nrf2-mediated oxidative stress and regulating the gut microbiota in mice

XL Liu, YC Zhao, HY Zhu, M Wu, YN Zheng, M Yang… - Food & Function, 2021 - pubs.rsc.org
Aging and aging-related metabolic complications are global problems that seriously
threaten public health. Taxifolin (TAX) is a novel health food and has been widely proved to …

[HTML][HTML] Prevention and treatment of cardiovascular diseases with plant phytochemicals: A review

RK Bachheti, LA Worku, YH Gonfa… - Evidence-Based …, 2022 - hindawi.com
Cardiovascular diseases (CVDs) are the world's leading killers, accounting for 30% deaths.
According to the WHO report, CVDs kill 17.9 million people per year, and there will be 22.2 …

[HTML][HTML] Antioxidant and anti-inflammatory activities of unexplored Brazilian native fruits

J Infante, PL Rosalen, JG Lazarini, M Franchin… - PLoS …, 2016 - journals.plos.org
Brazilian native fruits are unmatched in their variety, but a poorly explored resource for the
development of food and pharmaceutical products. The aim of this study was to evaluate the …