Recent advances of imidazole-containing derivatives as anti-tubercular agents

YL Fan, XH Jin, ZP Huang, HF Yu, ZG Zeng… - European journal of …, 2018 - Elsevier
Tuberculosis still remains one of the most common, communicable, and leading deadliest
diseases known to mankind throughout the world. Drug-resistance in Mycobacterium …

Targeting mycobacterial membranes and membrane proteins: Progress and limitations

G Kumar, S Kapoor - Bioorganic & medicinal chemistry, 2023 - Elsevier
Among the various bacterial infections, tuberculosis continues to hold center stage. Its
causative agent, Mycobacterium tuberculosis, possesses robust defense mechanisms …

Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs

A Chauhan, M Kumar, A Kumar, K Kanchan - Life sciences, 2021 - Elsevier
Tuberculosis is one of the deadliest infectious diseases existing in the world since ancient
times and still possesses serious threat across the globe. Each year the number of cases …

Recent developments in biological aspects of chalcones: the odyssey continues

A Rani, A Anand, K Kumar, V Kumar - Expert opinion on drug …, 2019 - Taylor & Francis
Introduction: Chalcones are attractive to synthetic chemists because they are easy to
prepare, have a large number of replaceable hydrogens, thereby having significant …

Fluoroquinolones structural and medicinal developments (2013–2018): Where are we now?

GARY Suaifan, AAM Mohammed - Bioorganic & medicinal chemistry, 2019 - Elsevier
Fluoroquinolones are considered one of the widely utilized antibiotics, specifically, with the
recent development of newer generations such as moxifloxacin, delafloxacin and …

Synthesis and evaluation of new quinazoline-benzimidazole hybrids as potent anti-microbial agents against multidrug resistant Staphylococcus aureus and …

S Malasala, MN Ahmad, R Akunuri, M Shukla… - European Journal of …, 2021 - Elsevier
Owing to the rapid rise in antibiotic resistance, infectious diseases have become serious
threat to public health. There is an urgent need to develop new antimicrobial agents with …

Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions

TM Dhameliya, KA Bhakhar, ND Gajjar, KA Patel… - Journal of Molecular …, 2022 - Elsevier
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

[HTML][HTML] Organoboron compounds: Effective antibacterial and antiparasitic agents

PS Coghi, Y Zhu, H Xie, NS Hosmane, Y Zhang - Molecules, 2021 - mdpi.com
The unique electron deficiency and coordination property of boron led to a wide range of
applications in chemistry, energy research, materials science and the life sciences. The use …

Potential of dry powder inhalers for tuberculosis therapy: facts, fidelity and future

P Mehta, C Bothiraja, S Kadam… - … cells, nanomedicine, and …, 2018 - Taylor & Francis
Tuberculosis (TB) is a contagious and airborne infectious disease caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of substantial research efforts, continuous …

[HTML][HTML] Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents

NG Bajad, SK Singh, SK Singh, TD Singh… - Current Research in …, 2022 - Elsevier
Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …