[HTML][HTML] Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians

SS Batah, AT Fabro - Respiratory medicine, 2021 - Elsevier
COVID-19 has quickly reached pandemic levels since it was first reported in December
2019. The virus responsible for the disease, named SARS-CoV-2, is enveloped positive …

Pathophysiology of sickle cell disease

P Sundd, MT Gladwin, EM Novelli - Annual review of pathology …, 2019 - annualreviews.org
Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

[HTML][HTML] Neutrophil extracellular traps mediate m6A modification and regulates sepsis-associated acute lung injury by activating ferroptosis in alveolar epithelial cells

H Zhang, J Liu, Y Zhou, M Qu, Y Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study

J Tian, X Yuan, J Xiao, Q Zhong, C Yang, B Liu… - The Lancet …, 2020 - thelancet.com
Background COVID-19 has spread globally. Epidemiological susceptibility to COVID-19 has
been reported in patients with cancer. We aimed to systematically characterise clinical …

Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19)

B Diao, C Wang, Y Tan, X Chen, Y Liu, L Ning… - Frontiers in …, 2020 - frontiersin.org
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health …

Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cells

X Qin, J Zhang, B Wang, G Xu, X Yang, Z Zou, C Yu - Autophagy, 2021 - Taylor & Francis
Zinc oxide nanoparticles (ZnONPs) hold great promise for biomedical applications. Previous
studies have revealed that ZnONPs exposure can induce toxicity in endothelial cells, but the …

Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury

Y Li, Y Cao, J Xiao, J Shang, Q Tan, F Ping… - Cell Death & …, 2020 - nature.com
Acute lung injury (ALI) is a life-threatening disorder with high rates of morbidity and mortality.
Reactive oxygen species and epithelial apoptosis are involved in the pathogenesis of acute …

Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial

MA Matthay, CS Calfee, H Zhuo… - The Lancet …, 2019 - thelancet.com
Background Treatment with bone-marrow-derived mesenchymal stromal cells (MSCs) has
shown benefits in preclinical models of acute respiratory distress syndrome (ARDS). Safety …

Role of angiopoietin-2 in vascular physiology and pathophysiology

RG Akwii, MS Sajib, FT Zahra, CM Mikelis - Cells, 2019 - mdpi.com
Angiopoietins 1–4 (Ang1–4) represent an important family of growth factors, whose activities
are mediated through the tyrosine kinase receptors, Tie1 and Tie2. The best characterized …

Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19

S Shibata, H Arima, K Asayama, S Hoshide… - Hypertension …, 2020 - nature.com
Abstract Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people …