Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of
cancer death. A complex disease arising from the interaction of environmental and host …

ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …

A multitude of dietary factors from dietary fat to macro and micronutrients intakes have been
associated with breast cancer, yet data are still equivocal. Therefore, utilizing data from the …

Cells of a multicellular organism are genetically homogeneous but structurally and
functionally heterogeneous owing to the differential expression of genes. Many of these …

Biology presents many wonders, but one of the most remarkable is how a complex
multicellular organism grows from a single cell. Until recently, the processes involved …

Recent studies have demonstrated the presence of microsatellite instability (MSI) in tumors
from patients with hereditary nonpolyposis colon cancer and in a subset of patients with …

Aberrant DNA methylation patterns, including global hypomethylation, gene-specific
hypermethylation/hypomethylation, and loss of imprinting (LOI), are common in acute …

DNA methylation is not just for basic scientists any more. There is a growing awareness in
the medical field that having the correct pattern of genomic methylation is essential for …

DNA methylation is known to play an important role in the regulation of gene expression in
eukaryotes. In this study, we assessed the extent and pattern of cytosine methylation in the …

Down syndrome is a complex genetic and metabolic disorder attributed to the presence of
three copies of chromosome 21. The extra chromosome derives from the mother in 93% of …