Lymphatic endothelial cells (LECs) lining lymphatic vessels develop specialized cell-cell
junctions that are crucial for the maintenance of vessel integrity and proper lymphatic …

Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …

The angiopoietin (ANGPT)–TIE2/TEK signaling pathway is essential for blood and lymphatic
vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a …

The lymphatic and blood vascular systems function in concert to regulate the tissue fluid
homeostasis of the body. The pumping force of the heart generates a hydrostatic pressure …

Intraluminal valves are required for the proper function of lymphatic collecting vessels and
large lymphatic trunks like the thoracic duct. Despite recent progress in the study of …

The efficient transport of blood and lymph relies on competent intraluminal valves that
ensure unidirectional fluid flow through the vessels. In the lymphatic vessels, lack of luminal …

Despite significant advances made in cancer treatment, the development of therapeutic
resistance to anticancer drugs represents a major clinical problem that limits treatment …

Primitive lymphatic vessels are remodeled into functionally specialized initial and collecting
lymphatics during development. Lymphatic endothelial cell (LEC) junctions in initial …

Primary congenital glaucoma (PCG) is a leading cause of blindness in children worldwide
and is caused by developmental defects in 2 aqueous humor outflow structures, Schlemm's …

Recently, messenger RNAs in eukaryotes have shown to associate with antisense (AS)
transcript partners that are often referred to as long noncoding RNAs (lncRNAs) whose …