Over more than a century of research has established the fact that sleep benefits the
retention of memory. In this review we aim to comprehensively cover the field of “sleep and …

Vortioxetine, a novel antidepressant for the treatment of major depressive disorder (MDD), is
a 5-HT 3, 5-HT 7 and 5-HT 1D receptor antagonist, 5-HT 1B receptor partial agonist, 5-HT …

The present study pooled the prevalence of sleep disturbances and depression in
community-dwelling older adults (mean age≥ 60 years) and quantified the strength of …

Dreaming has fascinated and mystified humankind for ages: the bizarre and evanescent
qualities of dreams have invited boundless speculation about their origin, meaning and …

Alcohol is a potent somnogen and one of the most commonly used “over the counter” sleep
aids. In healthy non-alcoholics, acute alcohol decreases sleep latency, consolidates and …

The “ascending reticular activating system” theory proposed that neurons in the upper
brainstem reticular formation projected to forebrain targets that promoted wakefulness. More …

During the last decade, several studies have shown that insomnia, rather than a symptom of
depression, could be a medical condition on its own, showing high comorbidity with …

This paper presents a theoretical review of rapid eye movement sleep with a special focus
on pontine-geniculate-occipital waves and what they might tell us about the functional …

Interleukin-1 beta (IL1) and tumor necrosis factor alpha (TNF) promote non-rapid eye
movement sleep under physiological and inflammatory conditions. Additional cytokines are …

To understand how arousal state impacts cerebral hemodynamics and neurovascular
coupling, we monitored neural activity, behavior, and hemodynamic signals in un …