Sarcopenia: an overview

E Marzetti, R Calvani, M Tosato, M Cesari… - Aging clinical and …, 2017 - Springer
Sarcopenia, the age-dependent loss of muscle mass and function, is a common condition
among older adults, and is associated with several adverse health outcomes. Owing to the …

Interventions for treating sarcopenia: a systematic review and meta-analysis of randomized controlled studies

Y Yoshimura, H Wakabayashi, M Yamada… - Journal of the American …, 2017 - Elsevier
Background Much interest has been focused on interventions for treating sarcopenia;
however, the effects have gained little evidence. Objective To analyze the effectiveness of …

Physical activity and exercise as countermeasures to physical frailty and sarcopenia

E Marzetti, R Calvani, M Tosato, M Cesari… - Aging clinical and …, 2017 - Springer
The identification of cost-effective interventions that improve the health status and prevent
disability in old age is one of the most important public health challenges. Regular physical …

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

TS Bowen, G Schuler, V Adams - Journal of cachexia …, 2015 - Wiley Online Library
Skeletal muscle provides a fundamental basis for human function, enabling locomotion and
respiration. Transmission of external stimuli to intracellular effector proteins via signalling …

Epidemiology of sarcopenia and insight into possible therapeutic targets

EM Dennison, AA Sayer, C Cooper - Nature Reviews Rheumatology, 2017 - nature.com
Musculoskeletal ageing is a major public health concern owing to demographic shifts in the
population. Sarcopenia, generally defined as the age-related loss of muscle mass and …

Mobility in older community-dwelling persons: a narrative review

E Freiberger, CC Sieber, R Kob - Frontiers in Physiology, 2020 - frontiersin.org
Due to the demographic changes and the increasing awareness of the role of physical
function, mobility in older age is becoming an important topic. Mobility limitations have been …

[HTML][HTML] Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via …

J Fan, X Yang, J Li, Z Shu, J Dai, X Liu, B Li, S Jia… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The quality control of skeletal muscle is a continuous requirement throughout the lifetime,
although its functions and quality present as a declining trend during aging process …

Sarcopenia: an overview on current definitions, diagnosis and treatment

F Landi, R Calvani, M Cesari, M Tosato… - Current Protein and …, 2018 - ingentaconnect.com
Sarcopenia, the progressive and generalized loss of skeletal muscle mass and
strength/function associated with aging, increases the risk of a vast array of adverse health …

Sarcopenia as a predictor of hospitalization among older people: a systematic review and meta-analysis

X Zhang, W Zhang, C Wang, W Tao, Q Dou, Y Yang - BMC geriatrics, 2018 - Springer
Background Previous cohort studies investigating the association between sarcopenia and
the risk of hospitalization have been inconsistent. We performed a meta-analysis to …

Age-related variations of muscle mass, strength, and physical performance in community-dwellers: results from the Milan EXPO survey

F Landi, R Calvani, M Tosato, AM Martone… - Journal of the American …, 2017 - Elsevier
Objectives Declining muscle mass and function are hallmarks of the aging process. The
preservation of muscle trophism may protect against various negative health outcomes. Age …