Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-
CoV-2 infection, especially in those with underlying comorbidities. AKI is associated with …

The kidney requires a large number of mitochondria to remove waste from the blood and
regulate fluid and electrolyte balance. Mitochondria provide the energy to drive these …

Purpose Current reports on acute kidney injury (AKI) in the intensive care unit (ICU) show
wide variation in occurrence rate and are limited by study biases such as use of incomplete …

Acute kidney injury (AKI) is a heterogeneous clinical syndrome that has multiple aetiologies,
variable pathogenesis and diverse outcomes. However, these heterogeneities are not …

Severity of AKI is determined by the magnitude of increase in serum creatinine level or
decrease in urine output. However, patients manifesting both oliguria and azotemia and …

Rationale: Acute kidney injury (AKI) is a common critical illness in the clinic and currently
lacks effective treatment options. Ischemia reperfusion injury (IRI) is a major pathogenic …

Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …

Nuclear factor κB (NF-κB) is a family of inducible transcription factors that plays a vital role in
different aspects of immune responses. NF-κB is normally sequestered in the cytoplasm as …

The previous conventional wisdom that survivors of acute kidney injury (AKI) tend to do well
and fully recover renal function appears to be flawed. AKI can cause end-stage renal …

Purpose The incidence, patient features, risk factors and outcomes of surgery-associated
postoperative acute kidney injury (PO-AKI) across different countries and health care …