MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene expression post-
transcriptionally by targeting either the 3′ untranslated or coding regions of genes. They …

Acute lymphoblastic leukemia, a heterogenous malignancy characterized by uncontrolled
proliferation of lymphoid progenitors and generally initiated in utero, is the most common …

Malignant transformation of T-cell progenitors causes T-cell acute lymphoblastic leukemia (T-
ALL), an aggressive childhood lymphoproliferative disorder. Activating mutations of Notch …

Acute lymphoblastic leukaemia (ALL) is an aggressive haematological tumour driven by the
malignant transformation and expansion of B-cell (B-ALL) or T-cell (T-ALL) progenitors. The …

Refractory disease and relapse remain the main causes of cancer therapy failure. Refined
risk stratification, treatment regimens and improved early diagnosis and detection of minimal …

Acute lymphoblastic leukemia (ALL) is the most common kind of pediatric cancer. Although
the cure rates in ALL have significantly increased in developed countries, still 15–20% of …

血清miR-922及miR-506对儿童急性淋巴细胞白血病诊断及预后判断的价值- PMC Back to Top
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Objectives To study the value of serum miR-922 and miR-506 expression levels in the
diagnosis and prognostic assessment of childhood acute lymphoblastic leukemia (ALL) …

Leukemia as one of the common cancers is still studied and needs improvement in
diagnosis and treatment. In this study, we examined the activity of hematopoietic stem cells …

Background Acute lymphoblastic leukemia (ALL) is a neoplastic disease that results from
multistep somatic mutations in a single lymphoid progenitor cell. MicroRNAs (miRNAs) are …