Gene-editing technology, from macromolecule therapeutics to organ transplantation: Applications, limitations, and prospective uses

GI Harisa, TM Faris, AY Sherif, RF Alzhrani… - International Journal of …, 2023 - Elsevier
Gene editing technologies (GETs) could induce gene knockdown or gene knockout for
biomedical applications. The clinical success of gene silence by RNAi therapies pays …

Barriers toward xenotransplantation in Arab World

M Ghazi, A Saleh, M Abdallah, D El Masri… - …, 2024 - Wiley Online Library
Organ transplant is a crucial therapeutic strategy offering a life‐saving and transformative
medical intervention. It provides an opportunity to improve their quality of life and increase …

Current state of clinical trials on xenograft

J El Masri, A Afyouni, M Ghazi, T Baroud… - …, 2023 - Wiley Online Library
Background Xenotransplantation is a worth investing branch of science, since it aims to fulfil
the demand on human cells, tissues and organs. Despite decades of consistent work in …

Ethical analysis of the first porcine cardiac xenotransplantation

C Gyngell, M Munsie, M Fujita, C Thiessen… - Journal of Medical …, 2024 - jme.bmj.com
In this article, we provide an ethical analysis of the first porcine cardiac xenotransplant,
performed in Maryland, USA in early 2022. David Bennett was offered the experimental …

Tensile strength of ostrich carotid artery decellularized with liquefied dimethyl ether and DNase: an effort in addressing religious and cultural concerns

H Kanda, K Oya, T Irisawa, M Goto - Arabian Journal of Chemistry, 2023 - Elsevier
In a previous report, we proposed a method for decellularizing ostrich carotid arteries by
removing lipids from the arteries using liquefied dimethyl ether (DME) instead of the …

[PDF][PDF] Tensile strength of ostrich carotid artery decellularized with liquefied dimethyl ether and DNase: An effort in addressing religious and cultural concerns

M Goto - Arabian Journal of Chemistry, 2023 - researchgate.net
In a previous report, we proposed a method for decellularizing ostrich carotid arteries by
removing lipids from the arteries using liquefied dimethyl ether (DME) instead of the …

[HTML][HTML] Comprehensive Interventions in End-Stage Cardiomyopathy: Mechanical Circulatory Support and Heart Transplantation

AM Cornea, G Rodriguez, AL Cornea - 2024 - intechopen.com
This chapter provides a comprehensive exploration of the primary indications for employing
mechanical circulatory support and heart transplantation in the treatment of end-stage …

[PDF][PDF] Genetically Engineered Transgenic Pig for Organ Donation Xenotransplantation

R Singh, B Sahoo, B Pradhan - researchgate.net
The increase life expectancy of human has led to a growing number of patients with end-
stage organ failure. But the increasing demands for organs aren't full filled due to shortage of …