Lung cancer accounts for the main proportion of malignancy-related deaths and most
patients are diagnosed at an advanced stage. Immunotherapy and targeted therapy have …

mRNA display is a powerful biological display platform for the directed evolution of proteins
and peptides. mRNA display libraries covalently link the displayed peptide or protein …

The nuclear medicine field has seen a rapid expansion of academic and commercial interest
in developing artificial intelligence (AI) algorithms. Users and developers can avoid some of …

68Ga-NOTA-WL12 is a peptide-based PET imaging agent. We conducted a first-in-human
study of 68Ga-NOTA-WL12 for PET to study the in vivo biodistribution, metabolism, radiation …

While the development of positron emission tomography (PET) radiopharmaceuticals
closely follows that of traditional drug development, there are several key considerations in …

Radionuclide molecular imaging of human epidermal growth factor receptor type 2 (HER2)
expression may enable a noninvasive discrimination between HER2-positive and HER2 …

Soft‐tissue sarcomas (STS) represent a group of rare and heterogeneous tumors associated
with several challenges, including incorrect or late diagnosis, the lack of clinical expertise …

Immunotherapy has transformed the treatment landscape of many cancers, with durable
responses in disease previously associated with a poor prognosis. Patient selection remains …

Although antibodies are well developed and widely used in cancer therapy and diagnostic
fields, some defects remain, such as poor tissue penetration, long in vivo metabolic …

Immune checkpoint inhibitor (ICI) therapy has emerged as a major treatment option for a
variety of cancers. Among the immune checkpoints addressed, the programmed death …