Respiratory sensations motivate humans to behaviorally modulate their breathing and are
the sensory urge component of the respiratory motivation-to-action neural system. Human …

Fastigial nucleus (FN) is the phylogenetically oldest nucleus in the cerebellum, a classical
subcortical motor coordinator. As one of the ultimate integration stations and outputs of the …

Background: Dyspnea is a common, distressing symptom of cardiopulmonary and
neuromuscular diseases. Since the ATS published a consensus statement on dyspnea in …

Background: Congenital central hypoventilation syndrome (CCHS) is characterized by
alveolar hypoventilation and autonomic dysregulation. Purpose:(1) To demonstrate the …

Breathing is maintained and controlled by a network of neurons in the brainstem that
generate respiratory rhythm and provide regulatory input. Central chemoreception, the …

Emotional trauma and psychological stress can precipitate cardiac arrhythmia and sudden
death through arrhythmogenic effects of efferent sympathetic drive. Patients with preexisting …

New Findings What is the topic of this review? The pathways in the brain by which visceral
information, in particular cardiopulmonary afferents, ascend to the cerebral cortex have been …

Objective The processes underlying sudden unexpected death in epilepsy (SUDEP) remain
elusive, but centrally mediated cardiovascular or respiratory collapse is suspected. Volume …

This study combined functional and structural magnetic resonance imaging techniques,
optimized for the human brainstem, to investigate activity in brainstem respiratory control …

The elusive nature of sudden unexpected death in epilepsy (SUDEP) has led to
investigations of mechanisms and identification of biomarkers of this fatal scenario that …