[HTML][HTML] The interaction between ferroptosis and lipid metabolism in cancer
D Li, Y Li - Signal transduction and targeted therapy, 2020 - nature.com
Ferroptosis is a new form of programmed cell death characterized by the accumulation of
iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that …
iron-dependent lethal lipid peroxides. Recent discoveries have focused on alterations that …
[HTML][HTML] A novel ferroptosis-related gene signature for overall survival prediction in patients with hepatocellular carcinoma
J Liang, D Wang, H Lin, X Chen, H Yang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, which makes the
prognostic prediction challenging. Ferroptosis, an iron-dependent form of regulated cell …
prognostic prediction challenging. Ferroptosis, an iron-dependent form of regulated cell …
Ferroptosis, radiotherapy, and combination therapeutic strategies
Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
K Bersuker, JM Hendricks, Z Li, L Magtanong, B Ford… - Nature, 2019 - nature.com
Ferroptosis is a form of regulated cell death that is caused by the iron-dependent
peroxidation of lipids,. The glutathione-dependent lipid hydroperoxidase glutathione …
peroxidation of lipids,. The glutathione-dependent lipid hydroperoxidase glutathione …
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
DM Kremer, BS Nelson, L Lin, EL Yarosz… - Nature …, 2021 - nature.com
Cancer metabolism is rewired to support cell survival in response to intrinsic and
environmental stressors. Identification of strategies to target these adaptions is an area of …
environmental stressors. Identification of strategies to target these adaptions is an area of …
Persister cancer cells: Iron addiction and vulnerability to ferroptosis
R Rodriguez, SL Schreiber, M Conrad - Molecular cell, 2022 - cell.com
Ferroptosis is a unique type of non-apoptotic cell death resulting from the unrestrained
occurrence of peroxidized phospholipids, which are subject to iron-mediated production of …
occurrence of peroxidized phospholipids, which are subject to iron-mediated production of …
Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11
A challenge in oncology is to rationally and effectively integrate immunotherapy with
traditional modalities, including radiotherapy. Here, we demonstrate that radiotherapy …
traditional modalities, including radiotherapy. Here, we demonstrate that radiotherapy …
Ferroptosis and its potential role in the physiopathology of Parkinson's Disease
L Mahoney-Sánchez, H Bouchaoui, S Ayton… - Progress in …, 2021 - Elsevier
Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …
characterised by motor impairments as well as non-motor symptoms. While dopamine …
Ferroptosis detection: from approaches to applications
Understanding the intricate molecular machinery that governs ferroptosis and leveraging
this accumulating knowledge could facilitate disease prevention, diagnosis, treatment, and …
this accumulating knowledge could facilitate disease prevention, diagnosis, treatment, and …
HCAR1/MCT1 regulates tumor ferroptosis through the lactate-mediated AMPK-SCD1 activity and its therapeutic implications
Y Zhao, M Li, X Yao, Y Fei, Z Lin, Z Li, K Cai, Y Zhao… - Cell reports, 2020 - cell.com
Ferroptosis is a recently discovered form of programed cell death caused by the
metabolically regulated lipid peroxidation and holds promise for cancer treatment, but its …
metabolically regulated lipid peroxidation and holds promise for cancer treatment, but its …